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Melanoma clinical trials in Portland, OR

15 studies for Melanoma are looking for participants at sites in and around Portland (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

RecruitingPhase 3
  • Kaiser Foundation Hospitals, Portland
  • Oregon Health and Science University, Portland
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

Pan-tumor MRD Study

RecruitingObservational study
  • Oregon Health & Science University (OHSU), Portland
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Legacy Emanuel Children's Hospital, Portland
  • Oregon Health and Science University, Portland
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Providence Cancer Center Oncology and Hematology Care- Eastside, Portland
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04895709

A Study of MGC026 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Providence Cancer Institute, Portland
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

RecruitingPhase 4
  • OHSU Knight Cancer Institute, Portland
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07405086

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

RecruitingPhase 2
  • USA15-0, Portland
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Kaiser Permanente Northwest, Portland
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Portland
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Observational Study of Iris Tumors

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT03809585

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

RecruitingPhase 1/2
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Feb 13, 2025 · NCT05669430

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • Kaiser Permanente Northwest - Oncology Clinic, Portland
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Portland

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.