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Mild Cognitive Impairment clinical trials in Massachusetts
29 studies for Mild Cognitive Impairment are looking for participants at sites in Massachusetts.
Cities in Massachusetts
Treating Insomnia in Mild Cognitive Impairment
- Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 60 and older · All sexes · Updated Nov 5, 2026 · NCT06687161A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
- Massachusetts General Hospital - Charlestown, Charlestown
- K2 Medical Research - Foxborough, Foxborough
- Neurology Center of New England, Foxborough
- and 1 more
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Nov 4, 2026 · NCT07589595A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
- Massachusetts General Hospital (MGH), Charlestown
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Oct 29, 2026 · NCT06297590Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab
- Massachusetts General Hospital, Boston
RecruitingPhase 2
Ages 25 to 50 · All sexes · Updated Oct 27, 2026 · NCT06136546A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
- Boston Center for Memory, Newton
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Oct 27, 2026 · NCT06976216Alzheimer's Tau Platform: Master Protocol
- Brigham and Women's Hospital Center for Alzheimer Research and Treatment, Boston
RecruitingPhase 2
Ages 50 to 80 · All sexes · Updated Oct 26, 2026 · NCT06957418EXercise-induced PhysioLogical Adaptations In Neurological Disorders
- Brigham and Women's Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT07883720Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
- Adams Clinical Boston, Boston
- Boston Center for Memory, Newton
- Adams Clinical Watertown, Watertown
RecruitingPhase 3
Ages 50 to 90 · All sexes · Updated Oct 19, 2026 · NCT07177352A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
- ActivMed Practices & Research, LLC, Methuen
- Adams Clinical - Watertown, Watertown
RecruitingPhase 4
Ages 50 and older · All sexes · Updated Oct 19, 2026 · NCT07633470LIFT: Life Improvement Trial
- Brigham and Women's Hospital, Boston
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Oct 15, 2026 · NCT06366724Cognitive Dysfunction in Chronic and Persistent Immune Thrombocytopenia
- Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06817395Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
- Massachusetts General Hospital, Boston
RecruitingPhase 2
Ages 55 and older · All sexes · Updated Oct 13, 2026 · NCT07236190A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
- Local Institution - 0080, Watertown
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Oct 8, 2026 · NCT06976203Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium
- Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 70 and older · All sexes · Updated Sep 14, 2026 · NCT06052397Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
- Massachusetts General Hospital, Boston
- Boston Medical Center, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04916210Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- VA Boston Healthcare System, Boston
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 30 to 90 · All sexes · Updated Sep 1, 2026 · NCT04124029Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
- Boston University Neuromotor Recovery Laboratory, Boston
RecruitingHealthy volunteers welcome
Ages 50 to 90 · All sexes · Updated Aug 13, 2026 · NCT07659964Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
- Massachusetts General Hospital, Charlestown
RecruitingHealthy volunteers welcome
Ages 50 to 80 · All sexes · Updated Jul 14, 2026 · NCT05904132Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline
- Massachusetts General Hospital, Boston
Recruiting
Ages 50 and older · All sexes · Updated Jul 7, 2026 · NCT06246929Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease
- Massachusetts General Hospital, Boston
RecruitingEarly phase 1Healthy volunteers welcome
Ages 40 to 99 · All sexes · Updated May 6, 2026 · NCT06538311Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD
- Massachusetts General Hospital, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Mar 6, 2026 · NCT05881239TMS for Cognitive Decline in Aging and Preclinical AD
- Massachusetts General Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 40 to 99 · All sexes · Updated Feb 20, 2026 · NCT06956300Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease
- Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Boston
RecruitingPhase 2
Ages 60 to 85 · All sexes · Updated Feb 12, 2026 · NCT06489548Study of ALTO-101 in Patients With Schizophrenia
- Site 5124, Belmont
RecruitingPhase 2
Ages 21 to 55 · All sexes · Updated Dec 26, 2025 · NCT06502964Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
- McLean Hospital, Belmont
RecruitingObservational study
Ages 18 to 89 · All sexes · Updated Nov 6, 2025 · NCT05245903MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction
- McLean Hospital, Belmont
RecruitingPhase 2/3
Ages 18 to 35 · All sexes · Updated Sep 25, 2025 · NCT06191965Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities
- Brigham and Women's Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 55 and older · All sexes · Updated May 25, 2025 · NCT06989619Mindfulness for Cognition in Early-stage Alzheimer's Disease
- VA Boston Healthcare System - Jamaica Plain Campus, Boston
RecruitingHealthy volunteers welcome
Ages 50 to 100 · All sexes · Updated Jan 27, 2025 · NCT06792877From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.