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Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline
Comorbidity of Chronic Pain and Early Cognitive Decline Among Older, Community-Based Black Adults: Comparative Effectiveness of Mindfulness-Based Cognitive Therapy With Walking (MBCT+w) vs Active Living Every Day (ALED)
Who can join
Ages 50 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Black adults, male and females, age 50 or older * Have nonmalignant musculoskeletal chronic pain for more than three months * Reports early cognitive decline (subjective and objective) * Telephone Interview for Cognitive Status-41 score greater than or equal to 31 * Functional Activities Questionnaire score less than 9 * English fluency/literacy * Free of concurrent psychotropic or pain medication for at least 2 weeks prior to initiation of treatment, OR stable on current psychotropic or pain medication for a minimum of 6 weeks and willing to maintain stable dose * Cleared by medical doctor for study participation and no self-reported concerns about physical functioning on the revised Physical Activity Readiness Questionnaire (PAR-Q; score 0) Exclusion Criteria: * Diagnosed with dementia or neurodegenerative disease * Regular use of nonpharmacological pain management * Diagnosed with serious mental illness or substance abuse * Current suicidal ideation on self-report * Engagement of regular exercise for more than 30 minutes daily * Unable to walk
About the study
The investigators aim to conduct a randomized controlled trial to compare two symptom-management programs for Black older adults with early cognitive decline (self-reported confirmed by testing) and chronic pain. The programs are Mindfulness-Based Cognitive Therapy with Walking (MBCT+w) and Active Living Every Day (ALED). The investigators will assess how each program may help in improving physical, cognitive, and emotional function. The investigators will also assess whether improvements in outcomes from the two programs are maintained through a 6-month follow-up.
What is being tested
- MBCT+w (behavioral)
- ALED (behavioral)
Sponsor: Massachusetts General Hospital · Participants: 400 · Started: Jan 10, 2025
Contact the study team
- Mallory Morehead, MPH · Phone: (978) 580-3153
- Adjoa Acquaah, BA · Phone: (617) 726-8103
Official record on ClinicalTrials.gov — NCT06246929
Locations in the U.S.
| Massachusetts | Massachusetts General Hospital, Boston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.