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Myelodysplastic Syndromes clinical trials in Durham, NC

14 studies for Myelodysplastic Syndromes are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Duke University Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05564390

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

RecruitingPhase 1
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06846606

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

RecruitingPhase 3
  • Unc Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06465953

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

RecruitingPhase 1/2
  • Duke University Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Up to age 22 · All sexes · Updated Aug 25, 2026 · NCT04726241

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

RecruitingPhase 1
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06656494

Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

RecruitingPhase 1/2
  • Duke Cancer Institute, Durham
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT05308264

Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

RecruitingPhase 1/2
  • Research Site, Durham
  • Research Site, Chapel Hill · 10 mi away
Ages 16 and older · All sexes · Updated Jul 20, 2026 · NCT07155226

Registry of Older Patients With Cancer

RecruitingObservational study
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill · 10 mi away
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT01137825

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

RecruitingPhase 2/3
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT04256317

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • Duke University, Durham
  • UNC Hospital, Chapel Hill · 10 mi away
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

RecruitingPhase 1
  • Duke Cancer Center, Durham
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT05143996

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chapel Hill · 10 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

RecruitingObservational study
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill · 10 mi away
Ages 18 to 120 · All sexes · Updated Oct 27, 2025 · NCT01137643

About Myelodysplastic Syndromes

Myelodysplastic Syndromes (MDS) are rare. They are sometimes found during a routine blood test. Learn symptoms, risk factors, and treatment options.

More about Myelodysplastic Syndromes on MedlinePlus

Myelodysplastic Syndromes trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.