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Heart Failure clinical trials in Durham, NC
25 studies for Heart Failure are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
Recruiting
- Duke University, Durham
Left vs Left Randomized Clinical Trial
Recruiting
- University of North Carolina, Chapel Hill · 10 mi away
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Recruiting
- University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
RecruitingObservational study
- Durham, Durham
A Study of LY3971297 in Participants With Heart Failure
RecruitingPhase 1
- University of North Carolina, Division of Cardiology, Chapel Hill · 10 mi away
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
RecruitingPhase 3
- Duke University Hospital, Durham
- Clinical and Translational Research Center - University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Recruiting
- Duke University Medical Center, Durham
ELEVATE-HFpEF Clinical Study
Recruiting
- Duke University Medical Center, Durham
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
RecruitingPhase 3
- Duke University Health System, Durham
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
RecruitingPhase 3
- Research Site, Durham
NORM-HF Pivotal Study
Recruiting
- University of North Carolina, Chapel Hill · 10 mi away
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
RecruitingPhase 3
- Research Site, Durham
- Research Site, Chapel Hill · 10 mi away
Alleviant ALLAY-HFrEF Study
Recruiting
- Duke University Hospital, Durham
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
RecruitingPhase 2
- Duke University, Durham
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
RecruitingPhase 3
- Research Site, Durham
- Research Site, Chapel Hill · 10 mi away
BiVACOR® Total Artificial Heart Early Feasibility Study
Recruiting
- Duke University Hospital, Durham
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
RecruitingObservational studyHealthy volunteers welcome
- Duke University Health System, Durham
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
RecruitingObservational study
- Duke University Health System, Durham
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
RecruitingPhase 3
- Duke University, Durham
Alleviant ALLAY-HF Study
Recruiting
- Duke University Hospital, Durham
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
RecruitingPhase 2
- Duke University Hospital, Durham
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Recruiting
- UNC Medical Center, Durham
- Duke University, Durham
Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction
Recruiting
- Duke, Durham
The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study
RecruitingPhase 2
- UNC Eastowne Kidney Transplant Clinic, Chapel Hill · 10 mi away
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
Recruiting
- Duke University Medical Center, Durham
About Heart Failure
Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.
More about Heart Failure on MedlinePlus
Heart Failure trials in other cities
- New York City, NY51 studies
- Boston, MA46 studies
- Dallas, TX42 studies
- Houston, TX35 studies
- Cleveland, OH31 studies
- Philadelphia, PA31 studies
- San Francisco, CA29 studies
- Chicago, IL28 studies
- Kansas City, MO25 studies
- St. Louis, MO24 studies
- Indianapolis, IN24 studies
- Atlanta, GA23 studies
Other studies in Durham
- Breast Cancer63 studies
- Cancer (all types)61 studies
- Non-Small Cell Lung Cancer42 studies
- Multiple Myeloma36 studies
- Acute Myeloid Leukemia34 studies
- Lung Cancer33 studies
- Metastatic Cancer33 studies
- Prostate Cancer32 studies
- Colorectal Cancer30 studies
- Ovarian Cancer28 studies
- Chronic Lymphocytic Leukemia28 studies
- Pancreatic Cancer24 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.