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Prostate Cancer clinical trials in Durham, NC
32 studies for Prostate Cancer are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
RecruitingPhase 2
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
DESTINY-PANTUMOUR04
RecruitingObservational study
- Research Site, Durham
Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer
RecruitingPhase 1/2
- Duke University Medical Center, Durham
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
RecruitingPhase 3
- Duke University Medical Center (location of scans), Durham
- Duke University Medical Center - Duke Cancer Center, Durham
- Duke University Medical Center - Duke University Hospital (location of scans), Durham
- and 1 more
High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers
RecruitingPhase 2
- Durham VA Medical Center, Durham, NC, Durham
Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
RecruitingPhase 2
- Durham VA Medical Center, Durham, NC, Durham
Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer
RecruitingPhase 1
- Duke University Medical Center, Durham
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- Duke University, Durham
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
RecruitingPhase 3
- Duke University Medical Center, Durham
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
RecruitingPhase 3
- Durham VA Medical Center, Durham
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
RecruitingPhase 3
- Durham VA Medical Center, Durham
- Duke University Medical Center, Durham
The Vanguard Study: Testing a New Way to Screen for Cancer
RecruitingHealthy volunteers welcome
- Durham VA Medical Center, Durham
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
- Durham VA Medical Center, Durham
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
RecruitingPhase 2
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
COMPASS Study for Metastatic Castration-resistant Prostate Cancer
RecruitingObservational study
- Duke University, Durham
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
RecruitingPhase 1
- Duke University Medical Center, Durham
A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC
RecruitingPhase 1/2
- Duke University medical center, Durham
A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
RecruitingPhase 2
- Duke University Medical Center - Duke Cancer Center, Durham
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Duke University, Durham
A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer
RecruitingPhase 1
- Duke Cancer Institute, Durham
Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer
RecruitingObservational study
- Duke University, Durham
A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
RecruitingPhase 1
- Duke Cancer Center, Durham
A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer
RecruitingPhase 1/2
- Duke University, Durham
Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology
RecruitingHealthy volunteers welcome
- University of North Carolina at Chapel Hill, Department of Radiation Oncology, Chapel Hill · 10 mi away
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
RecruitingPhase 4
- Duke University Medical Center, Durham
International Registry for Men With Advanced Prostate Cancer (IRONMAN)
RecruitingObservational study
- Durham VA Medical Center, Durham
- Duke Cancer Network, Durham
- Duke University, Durham
- and 1 more
Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer
RecruitingPhase 2/3
- Durham VA Medical Center, Durham, NC, Durham
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
RecruitingPhase 1
- Duke Cancer Institute, Durham
A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
RecruitingPhase 1
- Duke Cancer Center, Durham
Designing Visual Tools to Enhance Cancer Surgeon Decision-making
Recruiting
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Chapel Hill · 10 mi away
ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials
RecruitingObservational study
- Duke University Medical Center, Durham
About Prostate Cancer
Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.
More about Prostate Cancer on MedlinePlus
Prostate Cancer trials in other cities
- New York City, NY103 studies
- Houston, TX76 studies
- Los Angeles, CA61 studies
- Boston, MA60 studies
- St. Louis, MO47 studies
- San Francisco, CA45 studies
- Chicago, IL45 studies
- Seattle, WA44 studies
- Philadelphia, PA44 studies
- Nashville, TN43 studies
- Baltimore, MD42 studies
- Washington, DC38 studies
Other studies in Durham
- Breast Cancer63 studies
- Cancer (all types)59 studies
- Non-Small Cell Lung Cancer39 studies
- Multiple Myeloma37 studies
- Metastatic Cancer33 studies
- Acute Myeloid Leukemia33 studies
- Lung Cancer32 studies
- Colorectal Cancer28 studies
- Ovarian Cancer27 studies
- Chronic Lymphocytic Leukemia27 studies
- Heart Failure26 studies
- Pancreatic Cancer25 studies
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.