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Non-Small Cell Lung Cancer clinical trials in Worcester, MA

14 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Worcester (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • UMass Memorial Medical Center - University Campus, Worcester
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04267848

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

RecruitingPhase 3
  • University of Massachusetts Memorial Medical Center, Worcester
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06472245

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • UMass Memorial Medical Center - University Campus, Worcester
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Reliant Medical Group, Worcester
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06890598

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

RecruitingPhase 3
  • Clinical Study Site, Worcester
  • Clinical Study Site, Milford · 17 mi away
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

RecruitingPhase 2/3
  • Dana-Farber Brigham and Womens Cancer Center at Milford Regional, Milford · 17 mi away
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • UMass Memorial Medical Center - University Campus, Worcester
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • UMass Memorial Medical Center - University Campus, Worcester
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06116682

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • UMass Memorial Medical Center - University Campus, Worcester
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Worcester
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Non-Small Cell Lung Cancer trials in other cities

Other studies in Worcester

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.