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Depression clinical trials in Worcester, MA

5 studies for Depression are looking for participants at sites in and around Worcester (within about 30 miles). Open a study to see who can join and how to contact the study team.

The Medically Tailored Groceries and Mental Health Study

Recruiting
  • UMass Chan Medical School, Worcester
  • Community Care Cooperative (C3), Worcester
  • UMass Memorial Health, Worcester
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07779707

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • University of Massachusetts Chan Medical Center, Worcester
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

RecruitingPhase 3
  • Vitalix Clinical, Inc, Worcester
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407

Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital

Recruiting
  • Worcester Recovery Center and Hospital, Worcester
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07359157

Social Needs Screening and Chronic Diseases Study (WE CARE)

RecruitingHealthy volunteers welcome
  • UMass Memorial Medical Center - Hahnemann Campus, Worcester
  • Family Health Center of Worcester, Worcester
  • UMass Memorial Medical Center -Benedict Family Medicine Clinic, Worcester
All ages · All sexes · Updated May 22, 2026 · NCT06903897

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Worcester

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.