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Obesity clinical trials in Massachusetts
46 studies for Obesity are looking for participants at sites in Massachusetts.
Cities in Massachusetts
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
- Boston Children's Hospital, Boston
RecruitingPhase 3
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
- Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
- Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
- Care Access - Quincy, Quincy
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07321886Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
- Brigham and Womens Hospital, Boston
- Btc of New Bedford, New Bedford
RecruitingPhase 3
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
- Research Site, North Dartmouth
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
- Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
- K2 Medical Research - Foxborough, Foxborough
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
- Brigham and Women's Hospital Diabetes Program, Boston
- MedVadis Research Corporation, Waltham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
- Knownwell, Needham
- Lucida Clinical Trials, New Bedford
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
- Skylight Health Research - Burlington, Burlington
- Care Access - Quincy, Quincy
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
- MedVadis Research Corporation, Waltham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07153471A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
- Boston Medical Center, Boston
- Knownwell, Needham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
- ACCOMPLISH-2 Research Site, Methuen
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression
- Massachusetts General Hospital, Boston
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Sep 11, 2026 · NCT07699445A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
- Knownwell, Needham
- Lucida Clinical Trials, New Bedford
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
- Metro Boston Clinical Partners, Brighton
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06857942Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
- Kailera Clinical Site, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284901Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · Women · Updated Aug 31, 2026 · NCT04839614PPDTM CorEvitasTM Obesity (OBR) Drug Effectiveness and Safety Registry
- CorEvitas, LLC, Waltham
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07598981Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity
- Exponent Boston, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07776678Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
- ACCOMPLISH-1 Research Site, Methuen
- ACCOMPLISH-1 Research Site, Needham
RecruitingPhase 3
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361The Osteoarthritis Prevention Study
- Brigham and Women's Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 50 and older · Women · Updated Jul 23, 2026 · NCT05946044Family-Based Weight Wellness Treatment Through Food is Medicine and Group Medical Visits in Pediatric and Adult Primary Care
- Tufts Medical Center, Boston
- Tufts University, Boston
Recruiting
Ages 12 to 17 · All sexes · Updated Jul 21, 2026 · NCT07717658Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food
- Cambridge Health Alliance, Sommerville
Recruiting
Ages 18 to 60 · All sexes · Updated Jul 16, 2026 · NCT06988462Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · Women · Updated Jul 13, 2026 · NCT06557005A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
- MedVadis Research Watertown, Waltham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07481630Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
- Brigham and Women's Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06138821Trans-nasal Endoscopy for Bariatric Patients
- Brigham and Women's Hospital, Boston
Recruiting
Ages 18 to 90 · All sexes · Updated Jun 25, 2026 · NCT06200961BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention
- Massachusetts General Hospital Cancer Center, Boston
Recruiting
Ages 18 to 80 · All sexes · Updated Jun 23, 2026 · NCT07162337Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity
- Massachusetts General Hospital, Boston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT05933499Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure
- Brigham and Women's Hospital, Boston
RecruitingObservational study
Ages 18 to 70 · All sexes · Updated Mar 2, 2026 · NCT05711758Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease
- Brigham and Women's Hospital, Boston
- Brigham and Women's Faulkner Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT05728697Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
- Massachusetts General Hospital Cancer Center, Boston
RecruitingPhase 1
Ages 18 to 50 · All sexes · Updated Feb 27, 2026 · NCT07095517Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
- New Balance Foundation Obesity Prevention Center, Boston
RecruitingHealthy volunteers welcome
Ages 9 to 12 · All sexes · Updated Jan 8, 2026 · NCT05464186Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment
- Diabetes Research Center, Boston
Recruiting
Ages 18 to 99 · All sexes · Updated Dec 30, 2025 · NCT07226947Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population
- Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 18 to 65 · All sexes · Updated Dec 24, 2025 · NCT05799222A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment
- Boston Children's Hospital (Part C only), Boston
- Brigham and Women's Hospital (Part C and Part D), Boston
RecruitingPhase 1/2Healthy volunteers welcome
Ages 12 to 65 · All sexes · Updated Dec 22, 2025 · NCT06239116Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment
- Brigham and Women's Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 10, 2025 · NCT06069622Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
- McLean Hospital, Belmont
- Brigham and Women's Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Dec 5, 2025 · NCT06105164From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.