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Opioid Overdose clinical trials in California
18 studies for Opioid Overdose are looking for participants at sites in California.
Cities in California
Buprenorphine Implementation at Syringe Service Programs to Reduce Overdoses
- Community Health Project Los Angeles (CHPLA), Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07631598A Study of Brenipatide in Participants With Opioid Use Disorder
- Ark Clinical Research - Fountain Valley, Fountain Valley
- Center on Substance Use and Health (CSUH), San Francisco
- UCSF Weill Institute for Neurosciences - Substance Use Disorders Clinic - Mission Bay, San Francisco
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07420283Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial
- Clinic Site A (blinded pending tribal approval), Arcata
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06565416Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.
- Highland Hospital Bridge Clinic at Alameda Health System, Oakland
- Outpatient Buprenorphine Induction Clinic, University of California, San Francisco, San Francisco
RecruitingPhase 4
Ages 18 to 99 · All sexes · Updated Sep 14, 2026 · NCT06323824A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder
- VA Long Beach Healthcare System, Long Beach, CA, Long Beach
- VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
- San Francisco VA Medical Center, San Francisco, CA, San Francisco
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT04375033EMS-Initiated Buprenorphine
- Alameda Health System, Oakland
RecruitingObservational study
All ages · All sexes · Updated Aug 27, 2026 · NCT07475728Behavioral Safety and Fentanyl Education: BSAFE
- San Francisco Department of Public Health, San Francisco
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07219082Identifying Biomarkers Related to Opioid Use and Pain Response Following Traumatic Injury and Surgery
- University of California, San Diego, La Jolla
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT07693270Telehealth vs In-Person Evaluation of Addiction Treatment After Visiting the Emergency Department
- El Centro Regional Medical Center Emergency Department, El Centro
- University of California Davis Emergency Department, Sacramento
- Olive View - UCLA Medical Center Emegency Department, Sylmar
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06961058Using Clinical Decision Support to Provide Social Risk-Informed Care for Opioid Use Disorder in the Emergency Department
- University of California, San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06872190Coordinating Outpatient bupreNorphiNe for Emergency Care and Continuing Treatment
- El Centro Regional Medical Center Emergency Department, El Centro
- University of California Irvine Emergency Department, Irvine
- Marshall Medical Center Emergency Department, Placerville
- and 1 more
Recruiting
Ages 14 and older · All sexes · Updated Jun 12, 2026 · NCT07024498Standard Versus High Dose ED-Initiated Buprenorphine Induction
- Highland Hospital, Oakland
- San Leandro Hospital, San Leandro
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated May 28, 2026 · NCT06494904Mapping Ibogaine Neural Dynamics in Opioid Use Disorder
- Susan Samueli Integrative Health Institute, University of California, Irvine, Irvine
RecruitingObservational study
Ages 21 to 70 · All sexes · Updated May 18, 2026 · NCT07226570CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial
- Stanford University Medical Center, Stanford
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated May 6, 2026 · NCT06027099Adaptive Interventions for Emergency Department Patients With Opioid Use Disorder
- Arrowhead Regional Medical Center, Colton
Recruiting
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT06827288Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits
- UCSD Health, La Jolla
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Feb 3, 2026 · NCT06387290Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder
- University of California, San Francisco, San Francisco
Recruiting
Ages 22 to 75 · All sexes · Updated Oct 28, 2025 · NCT07214467Families Left Behind
- San Diego County Medical Examiner Office, San Diego
Recruiting
Ages 18 and older · All sexes · Updated Aug 21, 2025 · NCT06854757From ClinicalTrials.gov, data retrieved Oct 3, 2026. Each study sets its own eligibility; the study team decides who can join.