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Opioid Overdose clinical trials in Pennsylvania

25 studies for Opioid Overdose are looking for participants at sites in Pennsylvania.

Cities in Pennsylvania

A Study of Brenipatide in Participants With Opioid Use Disorder

  • Adams Clinical Philadelphia, Philadelphia
  • Penn Medicine: University of Pennsylvania Health System, Philadelphia
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07420283

Teaching Health Resilience in a Hospital Setting: A Peer-led Intervention

  • UPMC Mercy Hospital, Pittsburgh
  • UPMC Presbyterian-Montefiore Hospital, Pittsburgh
  • UPMC Shadyside Hospital, Pittsburgh
Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06843213

A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

  • Philadelphia MultiService Center, Philadelphia, PA, Philadelphia
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT04375033

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

  • AHN Allegheny General Hospital, Pittsburgh
Recruiting
Ages 22 to 65 · All sexes · Updated Aug 31, 2026 · NCT04354077

GLP-1R Agonist Treatment for Opioid Use Disorder

  • Pennsylvania Psychiatric Institute, Harrisburg
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 28, 2026 · NCT06548490

Ketones for Opioid Craving

  • Caron Pennsylvania Addiction Treatment and Rehab Center, Wernersville
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 25, 2026 · NCT07128524

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

  • UPMC Magee-Womens Hospital, Pittsburgh
RecruitingObservational study
Ages 18 and older · Women · Updated Aug 6, 2026 · NCT05942313

Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT

  • Hospital of the University of Pennsylvania (HUP), Philadelphia
  • University of Pennsylvania, Philadelphia
Recruiting
All ages · Women · Updated Jul 28, 2026 · NCT06969261

UnityPhilly Response App for Overdose Reversal

  • Drexel University, Philadelphia
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 20, 2026 · NCT06466005

Autobiographical Memory in Opioid Use Disorder

  • University of Pennsylvania, Philadelphia
RecruitingHealthy volunteers welcome
Ages 18 to 60 · All sexes · Updated Jul 10, 2026 · NCT06643988

Rapid Outpatient Low-dose Initiation of Buprenorphine for OUD With Fentanyl Use

  • University of Pennsylvania Center for Studies of Addiction, Philadelphia
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06379984

Psilocybin on Brain Mechanisms of Motivation in OUD

  • University of Pennsylvania, Philadelphia
RecruitingPhase 2
Ages 18 to 60 · All sexes · Updated Jul 9, 2026 · NCT06810310

An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care (SUPPORT)

  • Hospital of the University of Pennsylvania, Philadelphia
  • Penn Center for Women's Behavioral Wellness, Philadelphia
  • Pennsylvania Hospital, Philadelphia
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT06576323

Acetazolamide in Central Sleep Apnea Patients Using Medication for Opioid Use Disorder

  • University of Pittsburgh, Pittsburgh
RecruitingPhase 2
Ages 18 to 100 · All sexes · Updated Jun 25, 2026 · NCT06521476

Machine-Learning Prediction and Reducing Overdoses With EHR Nudges

  • University of Pittsburgh, Pittsburgh
Recruiting
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06806163

Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder

  • UPMC Presbyterian, Pittsburgh
Recruiting
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT07079826

Preoperative Opioid Tapering Before Spine Surgery

  • Thomas Jefferson University Hospital, Philadephia
Recruiting
Ages 18 and older · All sexes · Updated Mar 24, 2026 · NCT07221786

Adolescent Outcomes of Post-operative Opioid EXposure

  • Children's Hospital of Philadelphia, Philadelphia
RecruitingObservational study
Ages 12 to 17 · All sexes · Updated Mar 18, 2026 · NCT06350409

Evaluation of a Peer Recovery Support Program Adapted to Target Retention in Clinic-based Medication for Opioid Use Disorder Treatment

  • Geisinger Clinic, Danville
Recruiting
Ages 18 to 89 · All sexes · Updated Feb 18, 2026 · NCT07197801

Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

  • UPMC Children's Hospital, Pittsburgh
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · Women · Updated Dec 18, 2025 · NCT03923374

Integrating Brain, Neurocognitive, and Computational Tools in OUD

  • University of Pennsylvania, Philadelphia
RecruitingObservational study
Ages 18 to 60 · All sexes · Updated Dec 4, 2025 · NCT06136247

NavSTAR Implementation Effectiveness Trial Across a Health System

  • Jefferson Health, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Dec 3, 2025 · NCT07262190

Wellcome Leap Psilocybin for OUD

  • University of Pennsylvania, Philadelphia
RecruitingPhase 2
Ages 18 to 60 · All sexes · Updated Oct 29, 2025 · NCT06786325

MethaLoad Dose-Finding Study

  • Penn Center for Studies of Addiction (CSA), Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 14, 2025 · NCT06877858

Opioid Treatment and Peer Recovery Support

  • Temple University, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated May 13, 2025 · NCT04978168

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.