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Overweight clinical trials in Pennsylvania

32 studies for Overweight are looking for participants at sites in Pennsylvania.

Cities in Pennsylvania

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

  • Clinical Renal Associates Ltd., Media
  • Suburban Research Associates, West Chester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07794579

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

  • Geisinger Clinic, Danville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • UPMC Children's Hospital of Pittsburgh, Pittsburgh
RecruitingPhase 3
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Thomas Jefferson University - Medicine/GI and Hepatology, Philadelphia
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Thomas Jefferson University - Medicine/GI and Hepatology, Philadelphia
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

  • Preferred Primary Care Physicians, Preferred Clinical Research (Ofc 18), Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, Scottdale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

  • Keystone Clinical Studies, Plymouth Meeting
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

  • Preferred Primary Care Physicians, Uniontown
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07321886

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

  • Heritage Valley Multispecialty Group Inc, Beaver
  • Capital Area Research LLC, Camp Hill
  • Abington Medical Specialists, Horsham
RecruitingPhase 3
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

  • Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair, Pittsburgh
  • Preferred Primary Care Physicians, Uniontown
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

  • AURORA-1 Clinical Site, Philadelphia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

  • AURORA-2 Clinical Site, Philadelphia
  • AURORA-2 Clinical Site, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

  • VA Pittsburgh Healthcare System, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351058

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

  • Frontier Clinical Research, LLC, Scottdale
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT06897475

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

  • Suburban Research Associates - West Chester Office, West Chester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

  • ACCOMPLISH-2 Research Site, Philadelphia
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

  • UPA Ctr Weight and Eating Dis, Philadelphia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07770841

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

  • Capital Area Research LLC, Newport
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684235

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

  • UPMC Child Hosp-Pittsburgh, Pittsburgh
RecruitingPhase 3
Ages 8 to 18 · All sexes · Updated Aug 31, 2026 · NCT07253285

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

  • Altoona Center for Clinical Research, Duncansville
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Aug 27, 2026 · NCT07575399

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

  • Research Site, Philadelphia
  • Research Site, Smithfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07784725

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

  • ACCOMPLISH-1 Research Site, Philadelphia
RecruitingPhase 3
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents

  • Drexel University, Philadelphia
RecruitingHealthy volunteers welcome
Ages 14 to 19 · Women · Updated Jul 20, 2026 · NCT06147973

Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes

  • University of Pittsburgh, Pittsburgh
Recruiting
Ages 18 to 45 · Women · Updated Jun 24, 2026 · NCT05124808

Healthy Mom Zone Gestational Weight Gain Management Intervention 2.0

  • Pennsylvania State University, University Park
RecruitingHealthy volunteers welcome
Ages 18 to 45 · Women · Updated Jan 16, 2026 · NCT05807594

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

  • UPMC Children's Hospital of Pittsburgh, Pittsburgh
RecruitingObservational studyHealthy volunteers welcome
Ages 12 to 17 · All sexes · Updated Dec 18, 2025 · NCT05277558

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.