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Parkinson's Disease clinical trials in Durham, NC

10 studies for Parkinson's Disease are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Buntanetap in Participants With PD

RecruitingPhase 2/3
  • Duke Department of Neurosurgery, Durham
Ages 40 to 85 · All sexes · Updated Sep 21, 2026 · NCT07284784

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

RecruitingPhase 2
  • Duke Neurological Disorders Clinic (Site #210), Durham
Ages 30 to 80 · All sexes · Updated Sep 10, 2026 · NCT07432958

Parkinson's Foundation PD GENEration Genetic Registry

RecruitingObservational study
  • University of North Carolina - Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04994015

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

RecruitingPhase 3
  • Duke University Medical Center, Durham
Ages 50 to 85 · All sexes · Updated Sep 3, 2026 · NCT07174310

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

RecruitingPhase 2
  • University of North Carolina - Chapel Hill, Chapel Hill · 10 mi away
Ages 40 to 80 · All sexes · Updated Aug 28, 2026 · NCT06680830

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

RecruitingPhase 3
  • Duke Neurological Disorders Clinic, Durham
Ages 45 to 75 · All sexes · Updated Aug 4, 2026 · NCT06944522

Apathy in Parkinson Disease TMS Study

Recruiting
  • UNC-Chapel Hill, Cassidy Lab, Chapel Hill · 10 mi away
Ages 55 to 80 · All sexes · Updated Jul 8, 2026 · NCT06087926

A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

RecruitingPhase 2
  • Duke University (Neurology), Durham
  • University of North Carolina (Neurology), Chapel Hill · 10 mi away
Ages 45 to 75 · All sexes · Updated Jun 29, 2026 · NCT06285643

Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

Recruiting
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 50 to 80 · All sexes · Updated Jun 25, 2026 · NCT05864157

Retinal Imaging in Neurodegenerative Disease

RecruitingObservational studyHealthy volunteers welcome
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT03233646

About Parkinson's Disease

Parkinson's disease (PD) is a movement disorder. It causes tremors, stiffness, and slow movement. It gets worse over time. Learn what can help.

More about Parkinson's Disease on MedlinePlus

Parkinson's Disease trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.