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Phenylketonuria clinical trials in Indianapolis, IN

6 studies for Phenylketonuria are looking for participants at sites in and around Indianapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-181 in Subjects With Phenylketonuria

RecruitingPhase 1
  • Indiana University, Indianapolis
Ages 18 to 69 · All sexes · Updated Sep 28, 2026 · NCT07241234

A Study of Sepiapterin in Participants With Phenylketonuria (PKU)

RecruitingPhase 3
  • Indiana University School of Medicine, Indianapolis
Up to age 9 · All sexes · Updated Aug 28, 2026 · NCT06302348

A Study of MZE782 in Adults With PKU

RecruitingPhase 2
  • Indiana University School of Medicine, Indianapolis
Ages 18 to 75 · All sexes · Updated Aug 20, 2026 · NCT07694440

Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

RecruitingPhase 4
  • Indiana University School of Medicine, Indianapolis
Ages 18 to 65 · All sexes · Updated Jun 17, 2026 · NCT07477691

A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)

RecruitingObservational study
  • Indiana University School of Medicine, Indianapolis
All ages · All sexes · Updated Mar 25, 2026 · NCT05813678

A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

RecruitingObservational study
  • Riley Children's Hospital/ Indiana University Health, Indianapolis
All ages · All sexes · Updated Mar 24, 2026 · NCT06305234

About Phenylketonuria

In phenylketonuria (PKU), your body can't process phenylalanine, an amino acid in most foods. Read about genetics, screening, and special diets.

More about Phenylketonuria on MedlinePlus

Phenylketonuria trials in other cities

Other studies in Indianapolis

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.