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Phenylketonuria clinical trials in Chicago, IL

6 studies for Phenylketonuria are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

RecruitingPhase 4
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Ages 18 to 65 · All sexes · Updated Nov 10, 2026 · NCT07477691

A Study of MZE782 in Adults With PKU

RecruitingPhase 2
  • Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago
Ages 18 to 75 · All sexes · Updated Oct 23, 2026 · NCT07694440

A Study of JNT-517 in Participants With Phenylketonuria (PKU)

RecruitingPhase 3
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Ages 4 and older · All sexes · Updated Oct 21, 2026 · NCT06971731

PheCheck™ Validation Study

RecruitingObservational study
  • Lurie Children's Hospital, Chicago
Ages 1 and older · All sexes · Updated Aug 25, 2026 · NCT07551921

A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)

RecruitingObservational study
  • Northwestern University, Chicago
All ages · All sexes · Updated Mar 25, 2026 · NCT05813678

A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

RecruitingObservational study
  • Northwestern University, Chicago
All ages · All sexes · Updated Mar 24, 2026 · NCT06305234

About Phenylketonuria

In phenylketonuria (PKU), your body can't process phenylalanine, an amino acid in most foods. Read about genetics, screening, and special diets.

More about Phenylketonuria on MedlinePlus

Phenylketonuria trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.