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Progressive Supranuclear Palsy clinical trials recruiting in the U.S.

14 studies for Progressive Supranuclear Palsy are recruiting participants at sites across the United States.

Progressive supranuclear palsy (PSP) is a rare brain disease. It causes problems with balance, eye movement, and walking. Learn about what can help.

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Recently updated studies

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

RecruitingObservational study
Ages 18 to 110 · All sexes · Updated Sep 17, 2026 · NCT03225144

The Progressive Supranuclear Palsy Clinical Trial Platform

RecruitingPhase 2
Ages 41 to 86 · All sexes · Updated Sep 16, 2026 · NCT07173803

Biofluid Research on Age-Related or Inherited Neurodegeneration

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07798700

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy

RecruitingPhase 3
Ages 41 to 81 · All sexes · Updated Jul 29, 2026 · NCT07498426

Neurologic Stem Cell Treatment Study

Recruiting
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT02795052

A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy

RecruitingHealthy volunteers welcome
Ages 35 and older · All sexes · Updated May 5, 2026 · NCT02605785

Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging

RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Jan 27, 2026 · NCT03872102

UPenn Observational Research Repository on Neurodegenerative Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT04715399

The CurePSP Genetics Program

RecruitingObservational studyHealthy volunteers welcome
Ages 35 and older · All sexes · Updated Jan 14, 2026 · NCT06647641

Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A

RecruitingEarly phase 1
Ages 40 to 85 · All sexes · Updated Dec 23, 2025 · NCT06932809

Transcranial Magnetic Stimulation in Progressive Supranuclear Palsy

Recruiting
Ages 40 to 85 · All sexes · Updated May 29, 2025 · NCT04468932

NYSCF Scientific Discovery Biobank

RecruitingObservational study
30 Days · All sexes · Updated Mar 3, 2025 · NCT06203106

Modifiable Variables in Parkinsonism (MVP)

RecruitingObservational study
Ages 19 and older · All sexes · Updated Mar 25, 2022 · NCT02194816

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.