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Prostate Cancer clinical trials in Virginia

53 studies for Prostate Cancer are looking for participants at sites in Virginia.

Cities in Virginia

Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial

  • Virginia Urology Center, Richmond
Recruiting
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06496256

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

  • Virginia Clinical Research, Norfolk
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  • University of Virginia Health System ( Site 0054), Charlottesville
  • Inova Schar Cancer Institute ( Site 0017), Fairfax
  • Virginia Cancer Specialists (VCS) ( Site 8004), Fairfax
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

  • Blue Ridge Cancer Care, Blacksburg
  • University of Virginia Comprehensive Cancer Center, Charlottesville
  • University of Virginia, Charlottesville
  • and 5 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

  • Virginia Cancer Specialists, Fairfax
  • Onco Hemato Asso of SW Virginia, Roanoke
RecruitingPhase 2/3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06780670

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

  • University of Virginia Cancer Center, Charlottesville
  • Virginia Cancer Specialists PC, Leesburg
  • Bon Secours Cancer Institute at Saint Francis, Midlothian
  • and 1 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

  • Research Site, Norfolk
  • Research Site, Roanoke
  • Research Site, Virginia Beach
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

  • Blue Ridge Cancer Care ( Site 0024), Roanoke
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

  • Virginia Oncology Associates - Hampton, Norfolk
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07493512

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • Virginia Cancer Specialists, Fairfax
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

  • Potomac Urology, Woodbridge
Recruiting
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

  • Augusta Health Center for Cancer and Blood Disorders, Fishersville
  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • VCU Massey Cancer Center at Hanover Medical Park, Mechanicsville
  • and 5 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

  • Investigational Site number: 404, Fairfax
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05997615

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

  • NEXT Oncology, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

  • University of Virginia Cancer Center, Charlottesville
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Chesapeake Regional Medical Center, Chesapeake
  • Augusta Health Center for Cancer and Blood Disorders, Fishersville
  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • and 7 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

The Vanguard Study: Testing a New Way to Screen for Cancer

  • Sentara Martha Jefferson Hospital, Charlottesville
  • Inova Schar Cancer Institute, Fairfax
  • Inova Fair Oaks Hospital, Fairfax
  • and 5 more
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

  • Hematology Oncology Associates of Fredericksburg Inc, Fredericksburg
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
  • and 1 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT06931340

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • Bon Secours Saint Francis Medical Center, Midlothian
  • Bon Secours Richmond Community Hospital, Richmond
  • and 4 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06632977

Prostate Active Surveillance Study

  • Eastern Virginia Medical School, Norfolk
RecruitingObservational study
Ages 21 and older · Men · Updated Sep 2, 2026 · NCT00756665

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

  • Virginia Cancer Specialists, Fairfax
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 24, 2026 · NCT07745361

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

  • Virginia Cancer Specialists PC, Fairfax
RecruitingPhase 1
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT04221542

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

  • NEXT Oncology - Virginia, Fairfax
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Aug 20, 2026 · NCT06785636

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

  • University of Virginia Cancer Center, Charlottesville
  • VCU Massey Comprehensive Cancer Center, Richmond
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

Water Vapor Ablation for Prostate Cancer: Long-Term Registry

  • Urology of Virginia, Virginia Beach
RecruitingObservational study
All ages · Men · Updated Aug 18, 2026 · NCT07455058

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • University of Virginia, Charlottesville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

  • University of Virginia Comprehensive Cancer Center, Charlottesville
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 17, 2026 · NCT06842498

PSMA PET Combined With MRI for the Detection of PCa

  • Urology of Virginia, Virginia Beach
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · Men · Updated Jul 23, 2026 · NCT07052214

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

  • University of Virginia Cancer Center, Charlottesville
  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • Bon Secours Saint Francis Medical Center, Midlothian
  • and 3 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

  • Virginia Oncology Associates, Fairfax
  • Virginia Cancer Specialists, Norfolk
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

  • Inova Schar Cancer Institute, Fairfax
Recruiting
Ages 18 and older · Men · Updated Jun 17, 2026 · NCT00969111

HER2 FPBMC in Patients With Metastatic Breast and Prostate Cancer (AM006)

  • University of Virginia, Charlottesville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07441889

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

  • Onco Hemato Asso of SW Virginia, Roanoke
RecruitingPhase 4
Ages 18 to 100 · Men · Updated Jun 4, 2026 · NCT05803941

TERPS Trial for de Novo Oligometastic Prostate Cancer

  • Bon Secours Cancer Institute at St. Francis, Midlothian
RecruitingPhase 2
Ages 18 and older · Men · Updated Jun 3, 2026 · NCT05223803

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

  • University of Virginia, Charlottesville
RecruitingObservational study
Ages 21 and older · Men · Updated May 22, 2026 · NCT03151629

Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)

  • University of Virginia, Charlottesville
Recruiting
Ages 18 and older · Men · Updated May 4, 2026 · NCT06429813

Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment

  • Bon Secours Saint Francis Medical Center, Midlothian
  • Bon Secours Cancer Institute at Reynolds Crossing, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
RecruitingPhase 3
Ages 18 and older · Men · Updated Apr 14, 2026 · NCT06235697

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

  • Hunter Holmes McGuire VA Medical Center, Richmond, VA, Richmond
RecruitingPhase 2/3
Ages 18 and older · Men · Updated Apr 8, 2026 · NCT04787744

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.