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Prostate Cancer clinical trials in Charlottesville, VA

15 studies for Prostate Cancer are looking for participants at sites in and around Charlottesville (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3
  • University of Virginia Health System ( Site 0054), Charlottesville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

RecruitingPhase 3
  • University of Virginia Comprehensive Cancer Center, Charlottesville
  • University of Virginia, Charlottesville
  • UVA Health Cancer Care Pantops, Charlottesville
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

RecruitingPhase 2
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Sentara Martha Jefferson Hospital, Charlottesville
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

RecruitingPhase 2
  • University of Virginia Comprehensive Cancer Center, Charlottesville
Ages 18 and older · Men · Updated Aug 17, 2026 · NCT06842498

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

HER2 FPBMC in Patients With Metastatic Breast and Prostate Cancer (AM006)

RecruitingPhase 1/2
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07441889

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

RecruitingObservational study
  • University of Virginia, Charlottesville
Ages 21 and older · Men · Updated May 22, 2026 · NCT03151629

Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)

Recruiting
  • University of Virginia, Charlottesville
Ages 18 and older · Men · Updated May 4, 2026 · NCT06429813

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

RecruitingPhase 1
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · Men · Updated Feb 4, 2026 · NCT04729114

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Charlottesville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Charlottesville

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.