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Rectal Cancer clinical trials in Illinois

12 studies for Rectal Cancer are looking for participants at sites in Illinois.

Cities in Illinois

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

  • Endeavor Health ( Site 2027), Evanston
  • Accellacare of Duly ( Site 2015), Lisle
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06997497

PRE-ISPY Phase I/II Oncology Platform Program

  • The University of Chicago Medicine Comprehensive Cancer Center, Chicago
  • UChicago Medicine Comprehensive Cancer Center at Silver Cross Hospital, New Lenox
  • UChicago Medicine Orland Park, Orland Park
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05868226

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

  • OSF Saint Anthony's Health Center, Alton
  • Illinois CancerCare-Bloomington, Bloomington
  • Illinois CancerCare-Canton, Canton
  • and 31 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07283939

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

  • OSF Saint Anthony's Health Center, Alton
  • John H Stroger Jr Hospital of Cook County, Chicago
  • Loyola University Medical Center, Maywood
  • and 3 more
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Family Communications After Genetic Testing

  • OSF Saint Anthony's Health Center, Alton
  • Illinois CancerCare-Bloomington, Bloomington
  • Illinois CancerCare-Canton, Canton
  • and 33 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

  • Rush-Copley Medical Center, Aurora
  • Northwestern University, Chicago
  • Carle at The Riverfront, Danville
  • and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06205485

Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3

  • City of Hope at Illinois Chicago Downtown, Chicago
  • City of Hope at Chicago, Zion
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT07595874

Integrated Cancer Repository for Cancer Research

  • Rush-Copley Cancer Care Center, Aurora
  • Rush-Copley Healthcare Center, Yorkville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer

  • The University of Chicago, Chicago
Recruiting
Ages 18 to 90 · All sexes · Updated Jun 15, 2026 · NCT05943210

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

  • Illinois Cancer Specialists, Arlington Heights
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576

Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

  • Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine University of Chicago Medicine, Chicago
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 49 · All sexes · Updated Apr 24, 2026 · NCT05732623

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Chicago
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.