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Rectal Cancer clinical trials in Chicago, IL

8 studies for Rectal Cancer are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Advocate Illinois Masonic Medical Center, Chicago
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

PRE-ISPY Phase I/II Oncology Platform Program

RecruitingPhase 1/2
  • The University of Chicago Medicine Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05868226

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Recruiting
  • John H Stroger Jr Hospital of Cook County, Chicago
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

RecruitingPhase 3
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06205485

Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3

RecruitingPhase 2
  • City of Hope at Illinois Chicago Downtown, Chicago
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT07595874

The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer

Recruiting
  • The University of Chicago, Chicago
Ages 18 to 90 · All sexes · Updated Jun 15, 2026 · NCT05943210

Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine University of Chicago Medicine, Chicago
Ages 18 to 49 · All sexes · Updated Apr 24, 2026 · NCT05732623

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chicago
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Rectal Cancer trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.