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Schizophrenia clinical trials in Massachusetts

22 studies for Schizophrenia are looking for participants at sites in Massachusetts.

Cities in Massachusetts

Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia

  • Neurocrine Clinical Site, Boston
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07227818

NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia

  • Neurocrine Clinical Site, Boston
  • Neurocrine Clinical Site, Watertown
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07114874

A Study of Brenipatide in Adult Participants With Schizophrenia

  • McLean Hospital, Belmont
  • Adams Clinical Watertown, Watertown
  • University of Massachusetts Chan Medical School, Worcester
RecruitingPhase 2
Ages 18 to 55 · All sexes · Updated Sep 22, 2026 · NCT07410507

A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents

  • Boston Children's Hospital, Boston
  • Local Institution - 0132, Lexington
  • Local Institution - 0059, Worcester
RecruitingPhase 3
Ages 5 to 17 · All sexes · Updated Sep 22, 2026 · NCT07424404

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)

  • Boston Children's Hospital, Boston
  • Local Institution - 0059, Worcester
RecruitingPhase 3
Ages 13 to 17 · All sexes · Updated Sep 4, 2026 · NCT07288567

A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

  • Clinical Site, Boston
  • Clinical Site, Watertown
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 1, 2026 · NCT07459647

Cerebellar Modulation of Cognition in Psychosis

  • McLean Hospital, Belmont
  • Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 to 55 · All sexes · Updated Aug 20, 2026 · NCT06107764

Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

  • Boston Medical Center, Boston
  • Mayflower Clinical, South Dartmouth
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07101094

Biomarkers to Enhance Early Schizophrenia Treatment

  • McLean, Belmont
RecruitingPhase 4
Ages 18 to 35 · All sexes · Updated Jul 31, 2026 · NCT06969755

Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness

  • Massachusetts General Hospital, Charlestown
RecruitingHealthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Jul 16, 2026 · NCT04940663

Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia

  • UMass Chan Medical School, Worcester
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated May 22, 2026 · NCT06174116

CLOZAPINE Response in Biotype-1

  • Beth Israel Deaconess Medical Center, Boston
RecruitingPhase 4
Ages 18 to 60 · All sexes · Updated May 11, 2026 · NCT04580134

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

  • McLean Hospital, Belmont
  • Beth Israel Deaconess Medical Center, Boston
RecruitingObservational study
Ages 18 to 40 · All sexes · Updated Mar 10, 2026 · NCT06740383

NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

  • Neurocrine Clinical Site, Watertown
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Mar 6, 2026 · NCT06963034

Enhanced Coordinated Specialty Care for Early Psychosis

  • McLean Hospital OnTrack Clinic, Belmont
  • Massachusetts General Hospital FEPP Clinic, Boston
  • Boston Medical Center WRAP, Boston
  • and 2 more
Recruiting
All ages · All sexes · Updated Feb 27, 2026 · NCT06071858

Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia

  • McLean Hospital, Belmont
Recruiting
Ages 18 to 55 · All sexes · Updated Jan 22, 2026 · NCT05343598

Study of ALTO-101 in Patients With Schizophrenia

  • Site 5124, Belmont
RecruitingPhase 2
Ages 21 to 55 · All sexes · Updated Dec 26, 2025 · NCT06502964

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

  • McLean Hospital, Belmont
RecruitingPhase 2/3
Ages 18 to 35 · All sexes · Updated Sep 25, 2025 · NCT06191965

Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations

  • Boston VA Healthcare System, Brockton, Brockton
Recruiting
Ages 18 to 55 · All sexes · Updated Sep 18, 2025 · NCT05299749

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

  • Massachusetts General Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 10, 2025 · NCT04296604

The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia

  • Massachusetts General Hospital, Charlestown
RecruitingHealthy volunteers welcome
Ages 18 to 45 · All sexes · Updated May 14, 2025 · NCT06386588

Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia

  • Reviva site, Boston
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Dec 19, 2024 · NCT05184335

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.