Home › Sickle Cell Disease › Alabama
Sickle Cell Disease clinical trials in Alabama
16 studies for Sickle Cell Disease are looking for participants at sites in Alabama.
Cities in Alabama
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
- University Of Alabama, Birmingham
RecruitingPhase 3
Ages 12 to 100 · All sexes · Updated Sep 28, 2026 · NCT06439082A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)
- University of Alabama at Birmingham, Birmingham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07187973A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
- Uni of Alabama at Birmingham, Birmingham
- Univer South Alabama Ped/Onc, Mobile
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
- University of Alabama Birmingham, Birmingham
RecruitingPhase 1/2Healthy volunteers welcome
Ages 12 to 55 · All sexes · Updated Sep 9, 2026 · NCT06546670SCD Stem Cell Mobilization and Apheresis Using Motixafortide
- University of Alabama at Birmingham, Birmingham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06442761A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD
- AMR Clinical, Mobile
RecruitingPhase 2/3
Ages 12 and older · All sexes · Updated Aug 18, 2026 · NCT05431088A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
- University of Alabama at Birmingham, Birmingham
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease
- University of Alabama at Birmingham- Site Number : 8400003, Birmingham
RecruitingPhase 3
Ages 10 to 65 · All sexes · Updated Jul 29, 2026 · NCT06975865Early Life Exposures Among Children With Sickle Cell Disease
- University of Alabama at Birmingham, Birmingham
Recruiting
Ages 18 to 50 · Women · Updated Jul 15, 2026 · NCT05377372Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study
- University Of Alabama, Birmingham
RecruitingPhase 4
6 Months – 100 Years · All sexes · Updated Jun 8, 2026 · NCT04657822Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease
- Children's of Alabama (MRD-HCT), Birmingham
- Children's of Alabama (NT-DMT), Birmingham
RecruitingObservational study
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389Cognitive Remediation Intervention to Prepare for Transition of Care
- University of Alabama at Birmingham, Birmingham
RecruitingPhase 2
Ages 10 to 18 · All sexes · Updated Feb 27, 2026 · NCT05336201A Long-term Follow-up Study in Patients Who Received BEAM-101
- University of Alabama at Birmingham, Birmingham
RecruitingObservational study
Ages 14 to 37 · All sexes · Updated Jan 28, 2026 · NCT07373639Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
- University of South Alabama Medical Center, Mobile
Recruiting
Ages 16 to 30 · All sexes · Updated Jan 7, 2026 · NCT06374238HPC Offered for PRESERVE Expansion
- University of Alabama, Birmingham, Birmingham
RecruitingObservational study
Ages 12 to 80 · All sexes · Updated Aug 28, 2025 · NCT07145411Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease
- University of Alabama, Birmingham (UAB), Birmingham
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 22, 2025 · NCT06385886From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.