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Soft Tissue Sarcoma clinical trials in St. Louis, MO

14 studies for Soft Tissue Sarcoma are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

RecruitingPhase 1/2
  • Washington University School of Medicine in St. Louis, St Louis
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
  • Siteman Cancer Center-South County, St Louis
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05711615

Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma

RecruitingPhase 1/2
  • Washington University in St. Louis, St Louis
Ages 12 to 40 · All sexes · Updated Sep 3, 2026 · NCT07725380

Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women

RecruitingObservational study
  • Washington University School of Medicine, St Louis
Ages 18 to 50 · Women · Updated Sep 2, 2026 · NCT06904365

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Infusion Center - Chippewa, St Louis
  • Mercy Hospital South, St Louis
  • Missouri Baptist Medical Center, St Louis
  • and 4 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

RecruitingPhase 1/2
  • Washington University Medical Center, St Louis
Up to age 30 · All sexes · Updated Aug 3, 2026 · NCT06239272

Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

RecruitingPhase 2
  • Washington University in St. Louis, St Louis
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT04040205

Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

RecruitingPhase 1
  • Zai Lab Site 02005, St Louis
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT07374848

Lead-212 PSV359 Therapy for Patients With Solid Tumors

RecruitingPhase 1/2
  • Saint Louis University, St Louis
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756

Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06957431

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

RecruitingPhase 1/2
  • Washington University Infusion Center Pharmacy, St Louis
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Propranolol for the Treatment of Kaposi Sarcoma in Adults

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT06445166

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

RecruitingObservational studyHealthy volunteers welcome
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Feb 20, 2026 · NCT04354064

About Soft Tissue Sarcoma

Soft tissue sarcoma refers to cancer that begins in the muscle, fat, vessels or tendons. It can cause a lump or swelling. See which treatments are available

More about Soft Tissue Sarcoma on MedlinePlus

Soft Tissue Sarcoma trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.