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Soft Tissue Sarcoma clinical trials in Boston, MA

18 studies for Soft Tissue Sarcoma are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

RecruitingPhase 1/2
  • Dana Farber Cancer Institute., Boston
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610

Anti-GD2 ADC M3554 in Advanced Solid Tumors

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06641908

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05732831

First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06644755

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05711615

Serial MRI Scans During Radiation Therapy

Recruiting
  • Brigham and Women Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04188535

Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention

Recruiting
  • Boston Children's Hospital, Boston
  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 15 to 39 · All sexes · Updated Aug 26, 2026 · NCT07662239

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06975293

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07059884

Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma

RecruitingObservational study
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT07377747

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

RecruitingObservational study
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT07675967

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

RecruitingPhase 1/2
  • Massachusetts General Hospital,, Boston
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Video Education With Result Dependent dIsclosure

Recruiting
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT05225428

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

RecruitingPhase 1/2
  • Boston Children's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
  • Brigham and Women's Hospital, Boston
Ages 12 to 49 · All sexes · Updated Feb 19, 2026 · NCT06709495

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT04370587

REtroperitoneal SArcoma Registry: an International Prospective Initiative

RecruitingObservational study
  • Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Feb 12, 2019 · NCT03838718

About Soft Tissue Sarcoma

Soft tissue sarcoma refers to cancer that begins in the muscle, fat, vessels or tendons. It can cause a lump or swelling. See which treatments are available

More about Soft Tissue Sarcoma on MedlinePlus

Soft Tissue Sarcoma trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.