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Type 2 Diabetes clinical trials in Massachusetts

29 studies for Type 2 Diabetes are looking for participants at sites in Massachusetts.

Cities in Massachusetts

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, North Dartmouth
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

  • Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

  • K2 Medical Research - Foxborough, Foxborough
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  • ActivMed Practices & Research, Methuen
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07064473

A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus

  • Elixia Health - Springfield - Elixia - PPDS, Springfield
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 15, 2026 · NCT07340320

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

  • Brigham & Women's Hospital, Boston
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 11, 2026 · NCT07415954

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

  • Elixia SISU BHR - Springfield, Springfield
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07296484

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

  • Research Site, Braintree
  • Research Site, New Bedford
  • Research Site, Worcester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07662135

A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

  • Research Site, Boston
  • Research Site, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT07662109

Vitamin D and Type 2 Diabetes - Treat-To-Target

  • Tufts Medical Center, Boston
RecruitingPhase 3
Ages 30 to 74 · All sexes · Updated Aug 18, 2026 · NCT07448974

Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

  • Joslin Diabetes Center, Boston
Recruiting
Ages 14 to 75 · All sexes · Updated Aug 3, 2026 · NCT07579702

Continuous Glucose Monitor Use in Pregnancy

  • University of Massachusetts Memorial Medical Center, Worcester
Recruiting
Ages 18 and older · Women · Updated Aug 3, 2026 · NCT05317585

Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes

  • Joslin Diabetes Center, Boston
Recruiting
Ages 18 to 75 · All sexes · Updated Aug 3, 2026 · NCT07521475

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

  • Massachusetts General Hospital, Boston
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Jul 8, 2026 · NCT06003153

Re-Engineered Discharge for Diabetes Care Transitions

  • UMASS Memorial Healthcare System, Worcester
Recruiting
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06869057

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

  • Brigham and Women's Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06138821

EVOC - EVs in Obesity and Cardiometabolic Disease

  • Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06408961

Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery

  • Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 89 · All sexes · Updated Jun 11, 2026 · NCT07011147

Nutrition+: Effect of a High-Protein Diabetes Formula on Body Composition in Type 2 Diabetes Patients Treated With Incretin Mimetics

  • Joslin Diabetes Center, Boston
Recruiting
Ages 18 to 75 · All sexes · Updated May 29, 2026 · NCT07271043

DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

  • Boston Children's/Joslin Diabetes Center/Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 8 to 15 · All sexes · Updated May 7, 2026 · NCT06525259

Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)

  • President and Fellows of Harvard College, T.H. Chan School, Boston
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT06251323

Boosting Emotional Well-being and Happiness in Outpatients Living With Diabetes

  • Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT05420051

NAD Augmentation in Diabetes Kidney Disease

  • Brigham and Women's Hospital, Boston
RecruitingPhase 2
Ages 30 and older · All sexes · Updated Apr 13, 2026 · NCT05759468

Diabetes Body Project 2

  • Joslin Diabetes Center, Boston
Recruiting
Ages 18 to 40 · Women · Updated Mar 12, 2026 · NCT07468188

Improving Diabetes Care With Strategies For Addressing Health-Related Social Needs and Community Partnerships

  • Boston Medical Center, Boston
Recruiting
Ages 18 and older · All sexes · Updated Dec 30, 2025 · NCT07043426

Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

  • Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 18 to 65 · All sexes · Updated Dec 24, 2025 · NCT05799222

RESET System Pivotal Trial (Rev F)

  • Brigham and Women's Hospital, Boston
Recruiting
Ages 22 to 65 · All sexes · Updated Jul 18, 2024 · NCT04101669

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.