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Type 2 Diabetes clinical trials in Boston, MA

20 studies for Type 2 Diabetes are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

RecruitingPhase 2
  • Brigham & Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated Sep 11, 2026 · NCT07415954

A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, Boston
  • Research Site, Boston
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT07662109

Vitamin D and Type 2 Diabetes - Treat-To-Target

RecruitingPhase 3
  • Tufts Medical Center, Boston
Ages 30 to 74 · All sexes · Updated Aug 18, 2026 · NCT07448974

Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

Recruiting
  • Joslin Diabetes Center, Boston
Ages 14 to 75 · All sexes · Updated Aug 3, 2026 · NCT07579702

Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes

Recruiting
  • Joslin Diabetes Center, Boston
Ages 18 to 75 · All sexes · Updated Aug 3, 2026 · NCT07521475

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

RecruitingPhase 4Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Jul 8, 2026 · NCT06003153

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Recruiting
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06138821

EVOC - EVs in Obesity and Cardiometabolic Disease

RecruitingObservational study
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06408961

Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 to 89 · All sexes · Updated Jun 11, 2026 · NCT07011147

Nutrition+: Effect of a High-Protein Diabetes Formula on Body Composition in Type 2 Diabetes Patients Treated With Incretin Mimetics

Recruiting
  • Joslin Diabetes Center, Boston
Ages 18 to 75 · All sexes · Updated May 29, 2026 · NCT07271043

DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

RecruitingObservational study
  • Boston Children's/Joslin Diabetes Center/Massachusetts General Hospital, Boston
Ages 8 to 15 · All sexes · Updated May 7, 2026 · NCT06525259

Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)

RecruitingHealthy volunteers welcome
  • President and Fellows of Harvard College, T.H. Chan School, Boston
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT06251323

NAD Augmentation in Diabetes Kidney Disease

RecruitingPhase 2
  • Brigham and Women's Hospital, Boston
Ages 30 and older · All sexes · Updated Apr 13, 2026 · NCT05759468

Boosting Emotional Well-being and Happiness in Outpatients Living With Diabetes

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT05420051

Diabetes Body Project 2

Recruiting
  • Joslin Diabetes Center, Boston
Ages 18 to 40 · Women · Updated Mar 12, 2026 · NCT07468188

Improving Diabetes Care With Strategies For Addressing Health-Related Social Needs and Community Partnerships

Recruiting
  • Boston Medical Center, Boston
Ages 18 and older · All sexes · Updated Dec 30, 2025 · NCT07043426

Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

RecruitingObservational study
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Dec 24, 2025 · NCT05799222

RESET System Pivotal Trial (Rev F)

Recruiting
  • Brigham and Women's Hospital, Boston
Ages 22 to 65 · All sexes · Updated Jul 18, 2024 · NCT04101669

About Type 2 Diabetes

Type 2 Diabetes, previously referred to as Adult Onset Diabetes, is the more common type. Risk factors include obesity and family history.

More about Type 2 Diabetes on MedlinePlus

Type 2 Diabetes trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.