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Vascular Malformations clinical trials in Philadelphia, PA

4 studies for Vascular Malformations are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 2 and older · All sexes · Updated Nov 12, 2026 · NCT06789913

24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
2 Months – 30 Years · All sexes · Updated Oct 19, 2026 · NCT07549646

24VA022; VATCH Alpelisib for TIE2/PIK3CA Pathway VAs

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 2 to 30 · All sexes · Updated Oct 19, 2026 · NCT07543822

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
All ages · All sexes · Updated Jul 17, 2026 · NCT06259292

Vascular Malformations trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.