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Von Hippel-Lindau Syndrome clinical trials recruiting in the U.S.
7 studies for Von Hippel-Lindau Syndrome are recruiting participants at sites across the United States.
Von Hippel-Lindau syndrome (VHL) is a rare genetic disease that causes tumors and cysts to grow in your body. Learn about symptoms and treatment.
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Recently updated studies
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Nov 13, 2026 · NCT04924075National Eye Institute Biorepository for Retinal Diseases
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 120 · All sexes · Updated Oct 26, 2026 · NCT01496625Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT07405164Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Oct 16, 2026 · NCT04074135Data Collection Protocol for Patients With Von Hippel Lindau Disease
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT05955014Familial Investigations of Childhood Cancer Predisposition
RecruitingObservational study
All ages · All sexes · Updated Jun 17, 2026 · NCT03050268MyVHL: Patient Natural History Study
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Apr 26, 2024 · NCT03749980From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.