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Alzheimer's Disease clinical trials in North Carolina

21 studies for Alzheimer's Disease are looking for participants at sites in North Carolina.

Cities in North Carolina

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

  • New Hope Clinical Research, Charlotte
  • AMC Research, LLC, Matthews
RecruitingPhase 2
Ages 55 and older · All sexes · Updated Sep 29, 2026 · NCT06540833

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

  • West Clinical Research, Morehead City
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Sep 28, 2026 · NCT06937229

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

  • Triad Clinical Trials - 515 College Rd, Greensboro
  • AMC Research, LLC - Flourish - PPDS, Matthews
  • West Clinical Research, Morehead City
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Sep 22, 2026 · NCT06585787

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

  • Triad Clinical Trials, Greensboro
RecruitingPhase 3
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease

  • West Clinical Research, Morehead City
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Sep 16, 2026 · NCT07011745

ADRC Clinical Cohort (Alzheimer's Disease)

  • Duke University, Durham
RecruitingObservational studyHealthy volunteers welcome
Ages 25 to 80 · All sexes · Updated Sep 3, 2026 · NCT06703541

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

  • New Hope Clinical Research, Charlotte
  • UNC Health REX Hospital, Raleigh
RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Sep 1, 2026 · NCT06808984

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

  • AMC Research, LLC ( Site 1006), Matthews
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Aug 26, 2026 · NCT07033494

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

  • Duke University, Durham
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Aug 24, 2026 · NCT06297590

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

  • AMC Research, LLC, Matthews
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Aug 20, 2026 · NCT06976216

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

  • Duke University Medical Center, Durham
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

  • Flourish Research, Matthews
RecruitingPhase 1/2
Ages 35 to 85 · All sexes · Updated Jul 10, 2026 · NCT05462106

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

  • Monroe Biomedical Research, Monroe
RecruitingPhase 3
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

  • UNC Hosp Invest Drug Serv Pharm, Chapel Hill
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Jun 26, 2026 · NCT07094516

Olfactory Biopsies

  • Duke University Health Center, Durham
Recruiting
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07021040

A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

  • Duke Early Phase Research Unit, Durham
RecruitingPhase 1Healthy volunteers welcome
Ages 45 to 85 · All sexes · Updated Jun 4, 2026 · NCT06657768

Late Onset Alzheimer's Disease

  • North Carolina State University, Raleigh
RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated May 18, 2026 · NCT05010603

Connect-Home: Alzheimer's Disease and Related Dementias

  • University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 19 and older · All sexes · Updated Mar 30, 2026 · NCT06840587

Wake Forest Alzheimer's Disease Clinical Core

  • Wake Forest Baptist Health, Winston-Salem
RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Mar 27, 2026 · NCT03140865

Retinal Imaging in Neurodegenerative Disease

  • Duke University Medical Center, Durham
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT03233646

Open-label Extension Study in Participants With Early Alzheimer's Disease

  • GSK Investigational Site, Matthews
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Feb 2, 2026 · NCT07105709

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.