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Cardiovascular Disease clinical trials in North Carolina
30 studies for Cardiovascular Disease are looking for participants at sites in North Carolina.
Cities in North Carolina
- Durham17 studies
- Winston-Salem14 studies
- Charlotte9 studies
- Raleigh5 studies
- Greensboro5 studies
- Asheville4 studies
- Greenville3 studies
- Wilmington3 studies
ELEVATE-HFpEF Clinical Study
- Duke University Medical Center, Durham
Recruiting
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)
- Carolinas Medical Center, Charlotte
- Wake Forest University Health Sciences, Winston-Salem
Recruiting
Ages 21 and older · All sexes · Updated Sep 30, 2026 · NCT05897632EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
- Cary Cardiology, Cary
- The University of North Carolina at Chapel Hill, Chapel Hill
- Physicians East, PA, Greenville
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)
- Atrium Health Wake Forest Baptist Medical Center, Winston-Salem
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 29, 2026 · NCT07585968Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
- Asheville Cardiology Associates Research Department, Asheville
- Novant Health Clinical Research/Heart & Vascular Institute, Charlotte
- Mecklenburg Heart Specialists, Charlotte
- and 6 more
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06909565Product Surveillance Registry
- Chapel Hill
- Charleston
- Durham
- and 3 more
RecruitingObservational study
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
- Clinical Trial Site, Durham
- Clinical Trial Site, Greenville
- Clinical Trial Site, High Point
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease
- Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07685938Zenith® Fenestrated+ Clinical Study
- University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429Observational Pharmaco-Epidemiology Research & Analysis
- Epividian, Durham
RecruitingObservational studyHealthy volunteers welcome
Ages 0 and older · All sexes · Updated Sep 11, 2026 · NCT03813862Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- Duke University, Durham
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
- Novant Health Heart Vas Inst, Charlotte
- Medication Management LLC, Greensboro
- Accellacare US Inc, Raleigh
- and 2 more
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
- Clinical Research Site, Greensboro
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- Asheville VA-Charles George VA Medical Center, Asheville
- University of North Carolina, Chapel Hill
- Atrium Health, Charlotte
- and 5 more
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206Cardiovascular Effects of Very Low Nicotine Content Cigarettes
- Wake Forest University Health Sciences, Winston-Salem
RecruitingEarly phase 1Healthy volunteers welcome
Ages 21 and older · All sexes · Updated Aug 28, 2026 · NCT05707871A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
- Wake Forest University Health Sciences, Winston-Salem
RecruitingObservational study
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
- Research Site, Asheville
- Research Site, Chapel Hill
- Research Site, Charlotte
- and 11 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
- Duke University Health System, Durham
- Moses H Cone Memorial Hospital, Greensboro
- Medication Management LLC, Greensboro
- and 6 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012Global Paradise System US Post Approval Study
- University of North Carolina at Chapel Hill School of Medicine, Chapel Hill
- Durham VA Health System, Durham
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD
- Wake Forest University Baptist Medical Center, Winston-Salem
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Aug 7, 2026 · NCT06813911PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- UNC Medical Center, Durham
- Duke University, Durham
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487SPYRAL GEMINI Pilot Study
- University of North Carolina (UNC) Memorial Hospital, Chapel Hill
Recruiting
Ages 18 to 80 · All sexes · Updated Jun 24, 2026 · NCT06907147Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- University of North Carolina at Chapel Hill, Chapel Hill
- Carolinas Medical Center, Charlotte
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195Sequential Multiple Assignment Randomized Trial to Reduce Food Insecurity
- Wake Forest University Health Sciences, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07031739Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial
- Wake Forest University Health Sciences, Winston-Salem
RecruitingPhase 2
Ages 40 to 75 · All sexes · Updated Feb 27, 2026 · NCT06488105PKP2-ACM Natural History Study
- Duke University, Durham
RecruitingObservational study
Ages 12 and older · All sexes · Updated Feb 27, 2026 · NCT06644742Beta-Blocker Influences on Inflammatory and Neural Responses to Stress
- Social Neuroscience and Health Laboratory, Chapel Hill
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 30 · All sexes · Updated Oct 29, 2025 · NCT06263452MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels
- NC Heart and Vascular Research, LLC, Raleigh
Recruiting
Ages 18 to 80 · All sexes · Updated Sep 11, 2025 · NCT06271590MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
- NC Heart and Vascular Research, LLC, Raleigh
Recruiting
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs
- Mission Health, Asheville
Recruiting
Ages 18 and older · All sexes · Updated May 21, 2024 · NCT06424119From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.