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Multiple Myeloma clinical trials in Charlotte, NC

21 studies for Multiple Myeloma are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

RecruitingPhase 3
  • Research Site, Charlotte
  • Research Site, Charlotte
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07391657

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

RecruitingPhase 1
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05652335

A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel

RecruitingPhase 2
  • Atrium Health, Charlotte
Ages 18 to 80 · All sexes · Updated Sep 25, 2026 · NCT07149857

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

RecruitingPhase 3
  • Levine Cancer Institute, Charlotte
  • Novant Health, Charlotte
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05552222

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

RecruitingPhase 4
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05201781

A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1/2
  • Atrium Health Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07116616

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

RecruitingPhase 2
  • Atrium Health's Levine Cancer Institute, Charlotte
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

RecruitingPhase 3
  • Levine Cancer Institute, Charlotte
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06615479

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

RecruitingPhase 1/2
  • Atrium Health Levine Cancer Institute /ID# 271510, Charlotte
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06953960

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

RecruitingPhase 3
  • Novant Health Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07555938

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

RecruitingPhase 1
  • Atrium Health, Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT05651932

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

RecruitingPhase 1/2
  • Research Site, Charlotte
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05850234

Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT

RecruitingPhase 3
  • Research Site, Charlotte
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT07764978

Pre-malignant States to Hematologic Malignancies in Firefighters

RecruitingObservational studyHealthy volunteers welcome
  • Levine Cancer Institute, Charlotte
Ages 40 to 49 · All sexes · Updated Jul 13, 2026 · NCT06870760

CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study

RecruitingObservational studyHealthy volunteers welcome
  • Atrium Health Levine Cancer, Charlotte
Ages 30 and older · All sexes · Updated Jul 13, 2026 · NCT06644625

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

RecruitingPhase 2
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT05145400

CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

RecruitingPhase 1
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 25, 2025 · NCT05722418

About Multiple Myeloma

Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. Discover symptoms, diagnostic tests, and treatments for myeloma.

More about Multiple Myeloma on MedlinePlus

Multiple Myeloma trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.