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Multiple Myeloma clinical trials in Chicago, IL

24 studies for Multiple Myeloma are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

RecruitingPhase 3
  • University of Illinois, Chicago
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07555938

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

RecruitingPhase 4
  • Northwestern University, Chicago
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05201781

Mosaic Trial for Stem Cell Transplant Recipients

Recruiting
  • Northwestern University Feinberg School of Medicine, Chicago
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06960993

Use of Isatuximab, Dexamethasone and Lenalidomide in a Go-Slow Fashion for Ultra-Frail Patients With Multiple Myeloma

RecruitingPhase 2
  • University of Illinois Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT06517017

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

RecruitingPhase 1
  • University of Chicago Medical Center /ID# 278863, Chicago
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT07409246

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

RecruitingPhase 1/2
  • Research Site, Chicago
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT05850234

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 2
  • Northwestern Memorial Hospital, Chicago
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT06297226

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 3
  • Rush University System for Health, Chicago
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07518186

Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma

RecruitingPhase 2
  • University of Chicago Medicine Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05789303

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

RecruitingPhase 2
  • Cancer Treatment Centers of America-Chicago, Chicago
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535

Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma

RecruitingPhase 2
  • University of Illinois at Chicago, Chicago
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05344833

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

RecruitingPhase 3
  • Advocate Illinois Masonic Medical Center, Chicago
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04566328

Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT

RecruitingPhase 3
  • Research Site, Chicago
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT07764978

Personalized Autologous Transplant for Multiple Myeloma

RecruitingPhase 1
  • University Illinois Chicago, Chicago
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT04483206

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

RecruitingPhase 1
  • University of Chicago, Chicago
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma (TRIgnite-1)

RecruitingPhase 1
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT05862012

Hypofractionation (Radiation) Trial for Multiple Myeloma

RecruitingPhase 1
  • The University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT06270888

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • Northwestern, Chicago
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Free From Maintenance Drug Therapy in Multiple Myeloma (The FREEDMM Trial) for Minimal Residual Disease (MRD

RecruitingPhase 1
  • University of Illinois Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Dec 18, 2025 · NCT05192122

About Multiple Myeloma

Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. Discover symptoms, diagnostic tests, and treatments for myeloma.

More about Multiple Myeloma on MedlinePlus

Multiple Myeloma trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.