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Metastatic Cancer clinical trials in Sioux Falls, SD

10 studies for Metastatic Cancer are looking for participants at sites in and around Sioux Falls (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

RecruitingPhase 3
  • Avera Cancer Institute Research, Sioux Falls
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07562152

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Sanford Cancer Center Oncology Clinic, Sioux Falls
  • Sanford USD Medical Center - Sioux Falls, Sioux Falls
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Avera Medical Group, Sioux Falls
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Avera Cancer Institute, Sioux Falls
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • Avera Cancer Institute- Research, Sioux Falls
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Sanford Cancer Center, Sioux Falls
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

RecruitingPhase 3
  • Research Site, Sioux Falls
Ages 18 to 130 · All sexes · Updated Sep 8, 2026 · NCT07647328

A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Avera Cancer Institute, Sioux Falls
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06803680

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

RecruitingPhase 3
  • Research Site, Sioux Falls
  • Research Site, Sioux Falls
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

RecruitingPhase 3
  • Sanford Health, Sioux Falls
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06757634

Metastatic Cancer trials in other cities

Other studies in Sioux Falls

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.