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Treatment-Resistant Depressive Disorder clinical trials in St. Louis, MO

5 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Lumateperone for Late-Life Depression

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
Ages 60 and older · All sexes · Updated Sep 16, 2026 · NCT07623135

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Recruiting
  • Washington University School of Medicine, St Louis
Ages 22 to 70 · All sexes · Updated Aug 28, 2026 · NCT06423430

NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits

RecruitingPhase 1Healthy volunteers welcome
  • Washington University School of Medicine, St Louis
Ages 18 to 65 · All sexes · Updated Apr 29, 2026 · NCT02994433

Disruptions of Brain Networks and Sleep by Electroconvulsive Therapy

RecruitingObservational study
  • Washington University School of Medicine/Barnes-Jewish Hospital, St Louis
Ages 21 to 65 · All sexes · Updated Mar 12, 2026 · NCT05905705

Treatment-Resistant Depressive Disorder trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.