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Alzheimer's Disease clinical trials in Charlotte, NC

8 studies for Alzheimer's Disease are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

RecruitingPhase 2
  • New Hope Clinical Research, Charlotte
  • AMC Research, LLC, Matthews · 10 mi away
Ages 55 and older · All sexes · Updated Sep 29, 2026 · NCT06540833

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

RecruitingPhase 3
  • AMC Research, LLC - Flourish - PPDS, Matthews · 10 mi away
Ages 55 to 90 · All sexes · Updated Sep 22, 2026 · NCT06585787

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

RecruitingPhase 2
  • New Hope Clinical Research, Charlotte
Ages 55 to 90 · All sexes · Updated Sep 1, 2026 · NCT06808984

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

RecruitingPhase 2
  • AMC Research, LLC ( Site 1006), Matthews · 10 mi away
Ages 50 to 85 · All sexes · Updated Aug 26, 2026 · NCT07033494

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

RecruitingPhase 3
  • AMC Research, LLC, Matthews · 10 mi away
Ages 60 to 85 · All sexes · Updated Aug 20, 2026 · NCT06976216

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

RecruitingPhase 1/2
  • Flourish Research, Matthews · 10 mi away
Ages 35 to 85 · All sexes · Updated Jul 10, 2026 · NCT05462106

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

RecruitingPhase 3
  • Monroe Biomedical Research, Monroe · 24 mi away
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582

Open-label Extension Study in Participants With Early Alzheimer's Disease

RecruitingPhase 2
  • GSK Investigational Site, Matthews · 10 mi away
Ages 50 to 85 · All sexes · Updated Feb 2, 2026 · NCT07105709

About Alzheimer's Disease

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

More about Alzheimer's Disease on MedlinePlus

Alzheimer's Disease trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.