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Alzheimer's Disease clinical trials in Indianapolis, IN

14 studies for Alzheimer's Disease are looking for participants at sites in and around Indianapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Dominantly Inherited Alzheimer Network (DIAN)

RecruitingObservational studyHealthy volunteers welcome
  • Indiana University-Indiana Alzheimer Disease Center, Indianapolis
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT00869817

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

Recruiting
  • Eskenazi Health, Indianapolis
Ages 65 and older · All sexes · Updated Oct 5, 2026 · NCT05643144

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

RecruitingPhase 4
  • Josephson Wallack Munshower Neurology P.C., Indianapolis
Ages 50 and older · All sexes · Updated Sep 25, 2026 · NCT07633470

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

RecruitingPhase 2
  • Indiana University Health Neuroscience Center, Indianapolis
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07589595

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

RecruitingPhase 3
  • Josephson Wallack Munshower Neurology, PC, Indianapolis
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203

A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD

RecruitingPhase 1
  • Clinical Trial Site, Indianapolis
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05231785

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

RecruitingPhase 2/3Healthy volunteers welcome
  • Indiana University School of Medicine, Indianapolis
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT05552157

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

RecruitingPhase 2/3Healthy volunteers welcome
  • Indiana University School of Medicine, Indianapolis
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06647498

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

RecruitingPhase 3
  • Care Access - South Indianapolis, Indianapolis
  • Josephson Wallack Munshower Neurology, PC, Indianapolis
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582

Trial-Ready Cohort-Down Syndrome (TRC-DS)

RecruitingObservational study
  • Indiana University, Indianapolis
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109

Late Onset Alzheimer's Disease

RecruitingObservational studyHealthy volunteers welcome
  • NCRAD at Indiana University, Indianapolis
Ages 55 and older · All sexes · Updated May 18, 2026 · NCT05010603

Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study

Recruiting
  • Indiana University, Indianapolis
Ages 40 to 75 · All sexes · Updated May 6, 2026 · NCT05573490

Nicotinic Acid for the Treatment of Alzheimer's Disease

RecruitingPhase 1/2
  • IU Health Neuroscience Center, Indianapolis
Ages 60 to 85 · All sexes · Updated Mar 5, 2026 · NCT06582706

I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms

Recruiting
  • IU Health, Indianapolis
  • Community Health Network, Indianapolis
Ages 18 and older · All sexes · Updated Nov 24, 2025 · NCT05733520

About Alzheimer's Disease

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

More about Alzheimer's Disease on MedlinePlus

Alzheimer's Disease trials in other cities

Other studies in Indianapolis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.