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Breast Cancer clinical trials in Florida
146 studies for Breast Cancer are looking for participants at sites in Florida.
Cities in Florida
- Tampa43 studies
- Miami42 studies
- Jacksonville40 studies
- Orlando23 studies
- Plantation14 studies
- Sarasota12 studies
- Gainesville12 studies
- St. Petersburg11 studies
- Cape Coral10 studies
- Lakeland8 studies
- Deltona8 studies
- Davie7 studies
- Clearwater6 studies
- Miami Beach6 studies
- Hollywood6 studies
- West Palm Beach6 studies
- Kendall5 studies
- Deerfield Beach5 studies
- Coral Springs4 studies
- Boca Raton4 studies
- Fort Lauderdale4 studies
- Palm Bay3 studies
- Doral3 studies
- Tallahassee3 studies
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- University of Miami - Sylvester Comprehensive Cancer Center, Miami
- Advent Health, Orlando
- Florida Cancer Specialists South, Port Charlotte
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
- Holy Cross Health, Fort Lauderdale
- Memorial Cancer Institute, Hollywood
- Jupiter Medical Center, Jupiter
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Oct 2, 2026 · NCT05827081Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
- Schulze Family Foundation Cancer Clinic - Bonita Health Center, Bonita Springs
- Morton Plant Hospital, Clearwater
- and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
- Florida Cancer Specialists & Research Institute - Fort Myers Cancer Center - Gladiolus, Fort Myers
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06760819A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
- AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
- Holy Cross Hospital, Fort Lauderdale
- The Oncology Institute, Lakeland
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07102381Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 45 · Women · Updated Oct 1, 2026 · NCT05557877A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
- Mayo Clinic Florida, Jacksonville
- Cancer Specialists of North Florida, Jacksonville
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06369285Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
- Helios CR Inc, Lakeland
- H. Lee Moffitt Cancer Center and Research Institute, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06324357The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07285044Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy
- University of Florida Proton Therapy Institute, Jacksonville
- Dwoskin Proton Therapy Center, Miami
- Miami Cancer Institute, Miami
RecruitingPhase 3
Ages 19 and older · Women · Updated Sep 29, 2026 · NCT05856773A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
- Research Site, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599A Phase 1 Study of IM-1617 in Participants With Advanced Cancer
- Florida Cancer Specialists & Research Institute - Sarasota Cattlemen, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07578571Study of AVZO-021 in Patients With Advanced Solid Tumors
- Avenzo Therapeutics Recruiting Site, Sarasota
- Avenzo Therapeutics Recruiting Site, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05867251A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
- AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0024), Altamonte Springs
- Comprehensive Hematology Oncology ( Site 0060), St. Petersburg
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07060807Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
- Baptist MD Anderson Cancer Center, Jacksonville
Recruiting
Ages 30 and older · Women · Updated Sep 25, 2026 · NCT02945579A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
- AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0044), Altamonte Springs
- Florida Cancer Specialists - South ( Site 7004), Fort Myers
- Bioresearch Partner ( Site 0072), Hialeah
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
- AdventHealth Altamonte Springs ( Site 0021), Altamonte Springs
- Orlando Health Cancer Institute ( Site 0011), Orlando
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312176The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
- Miami Cancer Institute, Miami
- Miami Cancer Institute, Plantation
RecruitingPhase 3
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT06377852A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
- Research Site, Altamonte Springs
- Research Site, Miami
- Research Site, Plantation
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06103864Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer
- Morton Plant Hospital - Baycare Health System, Clearwater
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05528133ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
- Mayo Clinic, Jacksonville
- Sylvester Comprehensive Cancer Center, Miami
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559A Study to Compare the Steady-State Bioavailability of Injectable Letrozole SIE and Oral Letrozole in Post-Menopausal Women With Hormone Receptor Positive Early Breast Cancer
- D&H National Research Centers INC (Investigational Site number USA-002), Margate
- United Medical Research (Investigational Site number USA-005), Port Orange
RecruitingPhase 1
Ages 18 to 80 · Women · Updated Sep 23, 2026 · NCT07401381Remotely-Delivered Cognitive Behavioral Stress Management for Breast Cancer (R-CBSM)
- University of Miami, Coral Gables
Recruiting
Ages 50 and older · Women · Updated Sep 23, 2026 · NCT07502352A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
- University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
- Clinical Trial Site, Tampa
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
- Baptist MD Anderson, Jacksonville
- Mayo Clinic Florida, Jacksonville
- Jupiter Medical Cancer, Jupiter
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07214532Precise Oncology Interventions in Nutrition and Training (OnPoint)
- University of Miami, Miami
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06534918A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
- AdventHealth Altamonte Springs, Altamonte Springs
- Clermont Oncology Center, Clermont
- Florida Oncology & Hematology, Fort Myers
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336A Study of LY4257496 in Participants With Cancer (OMNIRAY)
- Moffitt, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
- AdventHealth Altamonte Springs, Altamonte Springs
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07287098A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
- Moffitt, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791A Study of JNJ-101684362 (HLD-0117) in Patients With Metastatic Breast Cancer
- Florida Cancer Specialists, Sarasota
RecruitingPhase 1
Ages 18 and older · Women · Updated Sep 21, 2026 · NCT07524855Women Informed to Screen Depending on Measures of Risk (Wisdom Study)
- TopLine MD Alliance, Miami
RecruitingHealthy volunteers welcome
Ages 30 to 74 · Women · Updated Sep 21, 2026 · NCT02620852Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer
- Baptist Alliance Miami Cancer Institute, Miami
RecruitingPhase 2
Ages 45 and older · Women · Updated Sep 21, 2026 · NCT04084730Identifying Patterns in the Breath of Individuals With Breast Cancer
- Mayo Clinic Breast Clinic, Jacksonville
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 74 · Women · Updated Sep 18, 2026 · NCT06512350ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
- Florida Cancer Specialists, Fort Myers
- Cancer Care Centers of Brevard, Inc, Palm Bay
- Sacred Heart Medical Oncology Group, Pensacola
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07173751A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
- Florida Cancer Specialists - Lake Nona, Orlando
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
- Hematology - Oncology Associates of the Treasure Coast, Port Saint Lucie
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06827236From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.