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Breast Cancer clinical trials in Orlando, FL
23 studies for Breast Cancer are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.
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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- Advent Health, Orlando
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 2
- AdventHealth Medical Group Oncology Research at Celebration, Kissimmee · 16 mi away
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
RecruitingPhase 3
- AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0024), Altamonte Springs · 9 mi away
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
RecruitingPhase 3
- AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0044), Altamonte Springs · 9 mi away
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
RecruitingPhase 3
- Orlando Health Cancer Institute ( Site 0011), Orlando
- AdventHealth Altamonte Springs ( Site 0021), Altamonte Springs · 9 mi away
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
RecruitingPhase 3
- Research Site, Altamonte Springs · 9 mi away
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- AdventHealth Altamonte Springs, Altamonte Springs · 9 mi away
- Clermont Oncology Center, Clermont · 24 mi away
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
RecruitingPhase 2
- AdventHealth Altamonte Springs, Altamonte Springs · 9 mi away
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
RecruitingPhase 1/2
- Florida Cancer Specialists - Lake Nona, Orlando
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
RecruitingPhase 3
- AdventHealth Orlando Infusion Center, Orlando
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
RecruitingPhase 1
- Sarah Cannon Research Institute - Lake Nona Florida, Orlando
A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer
RecruitingPhase 1
- Cancer Centers of Florida, Ocoee · 10 mi away
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
RecruitingPhase 3
- AdventHealth, Altamonte Springs · 9 mi away
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- AdventHealth Orlando, Orlando
- Orlando Health Cancer Institute, Orlando
- AdventHealth Altamonte, Altamonte Springs · 9 mi away
- and 1 more
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- Advent Health - Orlando, Orlando
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
RecruitingPhase 3
- AdventHealth Orlando, Orlando
- Orlando Health Cancer Institute, Orlando
- AdventHealth Altamonte, Altamonte Springs · 9 mi away
- and 1 more
A Study of DB-1310 in Advanced/Metastatic Solid Tumors
RecruitingPhase 1/2
- Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
RecruitingPhase 1/2
- Florida Cancer Specialists, Orlando
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
RecruitingObservational study
- AdventHealth East Altamonte Oncology and Hematology, Altamonte Springs · 9 mi away
Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots
RecruitingObservational studyHealthy volunteers welcome
- Adventhealth, Orlando
UCF MammoChat: Image Repository
RecruitingObservational studyHealthy volunteers welcome
- University of Central Florida, Orlando
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
RecruitingPhase 1
- Florida Cancer Specialists, Orlando
A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors
RecruitingPhase 1
- Exelixis Clinical Site #8, Orlando
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY134 studies
- Houston, TX126 studies
- Boston, MA111 studies
- Nashville, TN80 studies
- Los Angeles, CA72 studies
- Edison, NJ68 studies
- St. Louis, MO64 studies
- Durham, NC63 studies
- Queens, NY63 studies
- Chicago, IL58 studies
- Philadelphia, PA56 studies
- Dallas, TX55 studies
Other studies in Orlando
- Non-Small Cell Lung Cancer44 studies
- Obesity31 studies
- Metastatic Cancer29 studies
- Overweight27 studies
- Alzheimer's Disease25 studies
- Type 2 Diabetes24 studies
- Cancer (all types)24 studies
- Ovarian Cancer22 studies
- Ulcerative Colitis22 studies
- Lung Cancer21 studies
- Colorectal Cancer19 studies
- Major Depressive Disorder19 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.