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Kidney Cancer (Renal Cell Carcinoma) clinical trials in St. Louis, MO

23 studies for Kidney Cancer (Renal Cell Carcinoma) are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Washington University Medicine, St Louis
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Infusion Center - Chippewa, St Louis
  • Mercy Hospital South, St Louis
  • Missouri Baptist Medical Center, St Louis
  • and 4 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma

RecruitingPhase 1/2
  • Washington University in St. Louis, St Louis
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05287945

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
  • Mercy Hospital South, St Louis
  • Siteman Cancer Center-South County, St Louis
  • and 5 more
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)

RecruitingPhase 3
  • Washington University School of Medicine ( Site 0114), St Louis
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07489495

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

RecruitingPhase 1/2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07293351

Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06863311

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

RecruitingPhase 2
  • Mercy Hospital South, St Louis
  • Mercy Hospital Saint Louis, St Louis
  • Cancer Care Center of O'Fallon, O'Fallon · 16 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05327686

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

RecruitingPhase 1/2
  • Siteman Cancer Center, St Louis
  • Barnes-Jewish Hospital, St Louis
  • Washington University School of Medicine - Siteman Cancer Center, St Louis
  • and 5 more
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07227415

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
  • Mercy Hospital South, St Louis
  • Siteman Cancer Center-South County, St Louis
  • and 6 more
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06661720

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site, St Louis
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06966024

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

RecruitingPhase 3
  • Missouri Baptist Medical Center, St Louis
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT07383441

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

RecruitingPhase 1
  • Washington University Medical Campus, St Louis
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT05856981

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

RecruitingPhase 3
  • Saint Louis Cancer and Breast Institute-South City, St Louis
  • Mercy Hospital South, St Louis
  • Missouri Baptist Medical Center, St Louis
  • and 4 more
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT04510597

Kidney Cancer (Renal Cell Carcinoma) trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.