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Healthy volunteer studies in Charlottesville, VA

43 studies at sites in and around Charlottesville accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

RecruitingPhase 1/2Healthy volunteers welcome
  • Charlottesville Medical Research- Site Number : 8400062, Charlottesville
Ages 60 and older · All sexes · Updated Sep 24, 2026 · NCT07734649

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Charlottesville
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.

RecruitingPhase 1/2Healthy volunteers welcome
  • Charlottesville Medical Research- Site Number : 8400016, Charlottesville
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07779408

Quality of End-of-Life Care for Children With Cancer

RecruitingObservational studyHealthy volunteers welcome
  • University of Virginia Cancer Center, Charlottesville
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07412002

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Sentara Martha Jefferson Hospital, Charlottesville
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents

RecruitingPhase 3Healthy volunteers welcome
  • Pediatric Research of Charlottesville, LLC, Charlottesville
15 Months – 17 Years · All sexes · Updated Aug 31, 2026 · NCT07660198

Sleep, Dreaming, and Virtual Reality for Mental Health

RecruitingEarly phase 1Healthy volunteers welcome
  • Contemplative Sciences Center, Charlottesville
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07408206

Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)

RecruitingPhase 4Healthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 21 to 60 · All sexes · Updated Aug 12, 2026 · NCT03883412

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 45 to 74 · Women · Updated Jul 31, 2026 · NCT05625659

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Optimizing Ultrasound-induced Anti-inflammation in Human Subjects

RecruitingHealthy volunteers welcome
  • University of Virginia, Division of Nephrology; Center for Immunity, Inflammation & Regenerative Medicine, Charlottesville
Ages 25 to 50 · All sexes · Updated Jul 21, 2026 · NCT05685108

Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females

RecruitingHealthy volunteers welcome
  • Student Health and Wellness Building - Department of Kinesiology, Charlottesville
Ages 45 to 75 · Women · Updated Jul 17, 2026 · NCT06480695

Psilocybin for Prolonged Grief Disorder

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 to 65 · All sexes · Updated Jun 23, 2026 · NCT06724289

CARRII Native Intervention Optimization Trial

RecruitingHealthy volunteers welcome
  • University of Virginia Fontaine Research Park, Charlottesville
Ages 18 to 44 · Women · Updated Jun 23, 2026 · NCT07547696

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

RecruitingObservational studyHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 15 to 55 · Women · Updated Jun 4, 2026 · NCT06030063

Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder

RecruitingPhase 4Healthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 to 50 · Women · Updated May 7, 2026 · NCT06704594

Impact of Obesity on Microvascular Insulin Action and Cardiorespiratory Fitness in Type 1 Diabetes

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 21 to 50 · All sexes · Updated May 7, 2026 · NCT07573228

4D-MRI for Precision Medicine

RecruitingObservational studyHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 to 82 · All sexes · Updated May 6, 2026 · NCT04657042

A Study to Learn About mRNA Vaccines Against Influenza in Adults

RecruitingPhase 2Healthy volunteers welcome
  • Charlottesville Medical Research Center, LLC, Charlottesville
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07431853

Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome

RecruitingPhase 4Healthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 21 to 60 · All sexes · Updated May 6, 2026 · NCT04575844

Kidney Function in People With Cystic Fibrosis in the Era of HEMT

RecruitingObservational studyHealthy volunteers welcome
  • University of Virginia Children's Hospital, Charlottesville
Ages 7 and older · All sexes · Updated May 4, 2026 · NCT06595420

Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated May 4, 2026 · NCT05701969

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT05660525

A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

RecruitingPhase 1Healthy volunteers welcome
  • Pediatric Research of Charlottesville, LLC ( Site 1012), Charlottesville
2 Months – 15 Months · All sexes · Updated Apr 17, 2026 · NCT07300267

A Global Study of the PETAL Consortium

RecruitingObservational studyHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06067347

Examining Valence-based Effects in Self-Monitoring Feedback Messages

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07292389

Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 30 to 55 · All sexes · Updated Mar 23, 2026 · NCT04791371

Dissolved Phase HXe-129 MRI: A Novel Biomarker to Quantify Pulmonary Pathology

RecruitingPhase 2/3Healthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 to 35 · All sexes · Updated Mar 17, 2026 · NCT06856525

Maternal Newborn Health Registry

RecruitingObservational studyHealthy volunteers welcome
  • University of Virgina, Charlottesville
All ages · All sexes · Updated Jan 21, 2026 · NCT01073475

HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT05784753

Clinical Validation of a Predictive Test for Postpartum Depression

RecruitingObservational studyHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 and older · Women · Updated Dec 3, 2025 · NCT06831968

A Study of a Test for Postpartum Depression at Home

RecruitingObservational studyHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 and older · Women · Updated Nov 28, 2025 · NCT07186309

Genetic Information Assistant in Telegenetics

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Sep 23, 2025 · NCT06089421

Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 10 to 17 · Women · Updated Aug 5, 2025 · NCT00929006

Hyperandrogenemia and Altered Day-night LH Pulse Patterns

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Virginia Clinical Research Unit, Charlottesville
Ages 10 to 17 · Women · Updated Aug 5, 2025 · NCT03068910

Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Virginia Clinical Research Unit, Charlottesville
Ages 18 to 30 · Women · Updated Aug 5, 2025 · NCT03401047

Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?

RecruitingEarly phase 1Healthy volunteers welcome
  • Center for Research in Reproduction, University of Virginia, Charlottesville
Ages 10 to 17 · Women · Updated Aug 5, 2025 · NCT04723862

Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 10 to 99 · All sexes · Updated Jun 19, 2025 · NCT06047041

Increasing Lean Protein Intake in Preschool-age Children and Assessing Effects on Cognition and Select Health Outcomes

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 2 to 5 · All sexes · Updated Mar 18, 2025 · NCT06882252

Bone Mineral Density Agreement Study Between EOSedge™ Versus Traditional DXA

RecruitingHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 20 and older · All sexes · Updated Feb 14, 2025 · NCT06659055

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

RecruitingObservational studyHealthy volunteers welcome
  • University of Virginia, Charlottesville
Ages 18 and older · All sexes · Updated Feb 28, 2024 · NCT01574053

Contrast-enhanced Spectral Mammography (CESM) Breast Cancer Screening

RecruitingHealthy volunteers welcome
  • UVA Breast Care Center, Charlottesville
Ages 40 to 69 · Women · Updated Nov 17, 2022 · NCT04904757

Hyperpolarized Xenon-129 MR Imaging of the Lung

RecruitingPhase 1/2Healthy volunteers welcome
  • Snyder Building 480 Ray C. Hunt Drive, Charlottesville
Ages 18 and older · All sexes · Updated Dec 10, 2020 · NCT04662658

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.