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Crohn's Disease clinical trials in Pittsburgh, PA

11 studies for Crohn's Disease are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT03816345

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • The Allegheny Health Network (AHN) Center for Digestive Health-Site Number: 8400107, Pittsburgh
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184931

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • The Allegheny Health Network (AHN) Center for Digestive Health-Site Number: 8400107, Pittsburgh
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184944

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

RecruitingPhase 4
  • Allegheny Health Network, Wexford · 13 mi away
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT06045754

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

RecruitingPhase 4
  • UPMC Children's Hospital of Pittsburgh, Pittsburgh
Ages 6 to 17 · All sexes · Updated May 27, 2026 · NCT05781152

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

RecruitingPhase 3
  • Children's Hospital of Pittsburgh, Pittsburgh
Ages 2 to 17 · All sexes · Updated May 5, 2026 · NCT04779320

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
  • UPMC, Pittsburgh
Ages 18 to 75 · All sexes · Updated Apr 27, 2026 · NCT06456593

COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

RecruitingObservational study
  • University of Pittsburgh Medical Center, Children's Hospital, Pittsburgh
Ages 1 to 18 · All sexes · Updated Apr 17, 2026 · NCT07198113

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

RecruitingObservational study
  • UPMC Children's Hospital of Pittsburgh, Pittsburgh
2 Months – 60 Years · All sexes · Updated Jan 13, 2026 · NCT04528355

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

RecruitingPhase 2
  • UPMC Children's Hospital of Pittsburgh, Pittsburgh
2 Months – 55 Years · All sexes · Updated Dec 15, 2025 · NCT01962415

Autologous Stem Cell Transplantation for Crohn's Disease

RecruitingPhase 1/2
  • UPMC Prebyterian- Adult Gastroenterology, Pittsburgh
  • Children's Hospital of Pittsburgh of UPMC-Bone Marrow Team, Pittsburgh
Ages 10 to 60 · All sexes · Updated Dec 15, 2025 · NCT00692939

About Crohn's Disease

Crohn's Disease can cause inflammation in any area from the mouth to the anus. Read about medicines, surgery or dietary management to treat symptoms.

More about Crohn's Disease on MedlinePlus

Crohn's Disease trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.