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Breast Cancer clinical trials in Greenville, SC

12 studies for Breast Cancer are looking for participants at sites in and around Greenville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

RecruitingPhase 3
  • Bon Secours St Francis Cancer Center, Greenville
Ages 18 to 100 · All sexes · Updated Oct 2, 2026 · NCT05827081

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Greenville Memorial Hospital, Greenville
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

RecruitingPhase 3
  • St Francis Cancer Center ( Site 0093), Greenville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Saint Francis Hospital, Greenville
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • and 2 more
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Cancer Institute - Eastside, Greenville
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

RecruitingPhase 1/2
  • Prisma Health - Upstate (ITOR)_Edenfield ( Site 0053), Greenville
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06686394

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Saint Francis Hospital, Greenville
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • and 2 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Greenville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

RecruitingPhase 3
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Cancer Institute - Eastside, Greenville
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

Near Infrared Spectroscopy (NIRS) as a Method for Measuring Oxidative Capacity of Skeletal Muscle Mitochondria in Breast Cancer and All Gynecological Cancer Patients

RecruitingObservational study
  • Prisma Health Cancer Institute, Greenville
Ages 20 and older · Women · Updated Nov 4, 2024 · NCT06672497

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Greenville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.