🔎 Trials Near Me

Home › Breast Cancer › Tennessee › Knoxville

Breast Cancer clinical trials in Knoxville, TN

9 studies for Breast Cancer are looking for participants at sites in and around Knoxville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

RecruitingPhase 3
  • Tennessee Cancer Specialists, Knoxville
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06982521

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

RecruitingPhase 3
  • Tennessee Cancer Specialists ( Site 7001), Knoxville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • University of Tennessee Medical Center, Knoxville
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

RecruitingPhase 3
  • Clinical Trial Site, Knoxville
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

RecruitingPhase 3
  • Tennessee Cancer Specialists, Knoxville
Ages 18 to 100 · All sexes · Updated Aug 6, 2026 · NCT05232916

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • University of Tennessee - Knoxville, Knoxville
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • University of Tennessee - Knoxville, Knoxville
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy

Recruiting
  • Thompson Proton Center, Knoxville
Ages 18 and older · Women · Updated Apr 8, 2025 · NCT06006806

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Knoxville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.