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Non-Small Cell Lung Cancer clinical trials in Ann Arbor, MI

26 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Ann Arbor (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

RecruitingPhase 2
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • Chelsea Hospital, Chelsea · 15 mi away
  • and 3 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07293247

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • University of Michigan Rogel Cancer Center, Ann Arbor
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea · 15 mi away
  • and 2 more
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

RecruitingPhase 3
  • Trinity Health Ann Arbor Hospital, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06881784

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • University of Michigan Health System, Ann Arbor
  • Trinity Health St Joseph Mercy Ann Arbor, Ypsilanti · 7 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06667076

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

RecruitingPhase 2
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03191149

A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

RecruitingPhase 1
  • University of Michigan Health Systems, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07140016

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • University of Michigan Medical School Rogel Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

RecruitingPhase 3
  • Clinical Study Site, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT04302025

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

RecruitingPhase 3
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor ( Site 9552), Ypsilanti · 7 mi away
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06422143

Gilteritinib for the Treatment of ALK NSCLC

RecruitingPhase 1
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT06225427

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

RecruitingPhase 1
  • University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 252010, Ann Arbor
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT04777994

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea · 15 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06116682

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea · 15 mi away
  • Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton · 18 mi away
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Repositioning Immunotherapy in VetArans With Lung Cancer

RecruitingPhase 2
  • VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06275360

A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung Cancer

RecruitingPhase 2
  • University of Michigan (Data Collection Only), Ann Arbor
Ages 18 and older · All sexes · Updated Feb 23, 2026 · NCT07428044

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

Recruiting
  • VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT02984761

EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer

RecruitingPhase 1/2
  • VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor
Ages 18 and older · All sexes · Updated Jan 27, 2026 · NCT05467748

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Ann Arbor
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Non-Small Cell Lung Cancer trials in other cities

Other studies in Ann Arbor

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.