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Kidney Cancer (Renal Cell Carcinoma) clinical trials in Pittsburgh, PA

15 studies for Kidney Cancer (Renal Cell Carcinoma) are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

RecruitingPhase 1
  • Research Site, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05536141

A Phase 1 Study of the Safety and Tolerability of CTX-10726

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07419841

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

RecruitingPhase 1/2
  • UPMC Cancer Center/Hillman Cancer Center ( Site 5017), Pittsburgh
Ages 18 to 120 · All sexes · Updated Oct 2, 2026 · NCT07049926

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #32, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • UPMC Hillman Cancer Center, Pittsburgh
  • UPMC-Passavant Hospital, Pittsburgh
  • UPMC-Saint Clair Hospital Cancer Center, Pittsburgh
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

RecruitingPhase 2
  • Allegheny General Hospital, Pittsburgh
  • UPMC-Magee Womens Hospital, Pittsburgh
  • UPMC-Saint Margaret, Pittsburgh
  • and 14 more
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05327686

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

RecruitingPhase 3
  • UPMC Hillman Cancer Center, Pittsburgh
  • UPMC-Passavant Hospital, Pittsburgh
  • UPMC-Saint Clair Hospital Cancer Center, Pittsburgh
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06661720

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043

Autologous Dendritic Cell Vaccine in Kidney Cancer

RecruitingPhase 2
  • UPMC Department of Urology, Pittsburgh
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05127824

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

RecruitingPhase 1
  • UPMC Hillman Cancer Ctr /ID# 225706, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT04777994

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

RecruitingPhase 1/2
  • University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT06413680

Patient Preference for Subcutaneous vs. Intravenous Immune Therapy

RecruitingPhase 2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT07223424

A Study of VET3-TGI in Patients With Solid Tumors

RecruitingPhase 1
  • UPMC- Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06444815

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

RecruitingPhase 3
  • UPMC-Saint Margaret, Pittsburgh
  • University of Pittsburgh Cancer Institute (UPCI), Pittsburgh
  • UPMC-Shadyside Hospital, Pittsburgh
  • and 9 more
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT04510597

Kidney Cancer (Renal Cell Carcinoma) trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.