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Melanoma clinical trials in Charlotte, NC

7 studies for Melanoma are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

RecruitingPhase 3
  • Levine Cancer Institute, Charlotte
  • Novant Health Cancer Institute, Charlotte
  • Novant Health Weisiger Cancer Institute - Charlotte, Charlotte
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

Pan-tumor MRD Study

RecruitingObservational study
  • Carolina Oncology Specialists, Charlotte
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • Carolina Biooncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Clinical Trial Site, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07749586

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Atrium Health Pineville/LCI-Pineville, Charlotte
  • Levine Cancer Institute-SouthPark, Charlotte
  • and 8 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Carolina BioOncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT07317505

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.