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Metastatic Cancer clinical trials in Aurora, CO

25 studies for Metastatic Cancer are looking for participants at sites in and around Aurora (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • UCHealth University of Colorado Hospital, Aurora
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

RecruitingPhase 1
  • University of Colorado Anschutz Medical Campus, Aurora
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Rocky Mountain Cancer Centers, LLP, Aurora
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

RecruitingPhase 1/2
  • Children's Hospital Colorado - Anschutz Medical Campus, Aurora
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • Anschutz Cancer Pavilion, Aurora
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

RecruitingPhase 1/2
  • Rocky Mountain Cancer Centers,LLP, Aurora
  • Clinical and Translational Research Center(CTRC), Aurora
  • University of Colorado Hospital - Anschutz Inpatient Pavilion (AIP), Aurora
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07227415

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • University of Colorado Health Hospital, Aurora
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • University of Colorado, Aurora
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743

BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Aurora
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07193511

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Colorado, Aurora
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

RecruitingPhase 1/2
  • Crinetics Study Site, Aurora
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07129252

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • University of Colorado - Aurora Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 12 and older · All sexes · Updated Jul 14, 2026 · NCT05533697

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT05384626

Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

RecruitingPhase 2/3
  • University of Colorado Hospital - Anschutz Cancer Pavilion, Aurora
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06947928

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06362369

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

RecruitingPhase 2/3
  • University of Colorado Hospital - Anschutz Cancer Pavilion(ACP), Aurora
All ages · All sexes · Updated Apr 2, 2026 · NCT06581406

Venetoclax Basket Trial for High Risk Hematologic Malignancies

RecruitingPhase 1
  • Children's Hospital Colorado, Aurora
Ages 1 to 40 · All sexes · Updated Mar 12, 2026 · NCT05292664

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • UCHealth Cancer Care - Anschutz Medical Campus, Aurora
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04900818

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

RecruitingPhase 3
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Feb 6, 2026 · NCT06127407

Intraperitoneal Paclitaxel With NALIRIFOX for Pancreatic Ductal Adenocarcinoma With Peritoneal Carcinomatosis

RecruitingPhase 1
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Feb 2, 2026 · NCT07030283

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Aurora
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of NX-1607 in Adults With Advanced Malignancies

RecruitingPhase 1
  • University of Colorado School of Medicine, Aurora
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT05107674

Metastatic Cancer trials in other cities

Other studies in Aurora

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.