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Colorectal Cancer clinical trials in Aurora, CO

32 studies for Colorectal Cancer are looking for participants at sites in and around Aurora (within about 30 miles). Open a study to see who can join and how to contact the study team.

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Rocky Mountain Cancer Centers, LLP, Aurora
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

RecruitingPhase 3
  • University of Colorado Denver Anschultz Medical Campus, Aurora
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

RecruitingPhase 1
  • University of Colorado Denver Anschultz Medical Campus, Aurora
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06663319

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

RecruitingPhase 1/2
  • University of Colorado Anschutz Medical Campus ( Site 0299), Aurora
  • University of Colorado Anschutz Medical Campus ( Site 0325), Aurora
  • University of Colorado Anschutz Medical Campus ( Site 0326), Aurora
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06428409

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

RecruitingPhase 3
  • UCHealth University of Colorado Hospital, Aurora
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

RecruitingPhase 1
  • UCHealth University of Colorado Hospital, Aurora
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06102902

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • University of Colorado Hospital-Anschutz Cancer Pavilion, Aurora
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

RecruitingPhase 1/2
  • GSK Investigational Site, Aurora
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07213609

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • University of Colorado - Aurora Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

RecruitingPhase 3
  • Sarah Cannon Research Institute Scri Oncology Partners, Aurora
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

RecruitingPhase 1
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT04929223

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

RecruitingPhase 1/2
  • UCHealth University of Colorado Hospital, Aurora
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07147231

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Rocky Mountain Regional VA Medical Center, Aurora
  • UCHealth University of Colorado Hospital, Aurora
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • University of Colorado, Aurora
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's Hospital Colorado, Aurora
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection

RecruitingObservational studyHealthy volunteers welcome
  • University of Colorado Denver, Aurora
Ages 18 to 99 · All sexes · Updated Aug 24, 2026 · NCT05517811

A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.

RecruitingPhase 2
  • University of Colorado Hospital- Anschutz Cancer Center Pavillion (ACP), Aurora
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07235293

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

RecruitingObservational study
  • University of Colorado Anschutz Medical Center, Aurora
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT05410977

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Colorado, Aurora
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer

RecruitingHealthy volunteers welcome
  • University of Colorado Hospital, Aurora
Ages 18 to 85 · All sexes · Updated Aug 14, 2026 · NCT07759921

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

Recruiting
  • University of Colorado, Aurora
Ages 65 to 82 · All sexes · Updated Aug 13, 2026 · NCT05612347

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • University of Colorado, Aurora
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07066657

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

RecruitingPhase 3
  • Rocky Mountain Cancer Centers, LLP, Aurora
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05253651

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • University of Colorado Hospital - Anschutz Cancer Pavilion (ACP), Aurora
  • University of Colorado Hospital, Aurora
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • University of Colorado - Aurora Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

LYL273 for Patients With Relapsed or Refractory mCRC

RecruitingPhase 1/2
  • University of Colorado Hospital - Anschutz Cancer Pavilion, Aurora
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT05319314

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06362369

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Rocky Mountain Cancer Centers-Aurora, Aurora
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Aurora

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.