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Melanoma clinical trials in Aurora, CO

18 studies for Melanoma are looking for participants at sites in and around Aurora (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Rocky Mountain Regional VA Medical Center, Aurora
  • UCHealth University of Colorado Hospital, Aurora
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

RecruitingPhase 3
  • Rocky Mountain Regional VA Medical Center, Aurora
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

RecruitingPhase 3
  • University of Colorado Cancer Center, Aurora
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT05727904

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

RecruitingPhase 3
  • UCHealth University of Colorado Hospital, Aurora
Ages 75 and older · All sexes · Updated Sep 24, 2026 · NCT07068074

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0182, Aurora
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • Rocky Mountain Cancer Centers-Aurora, Aurora
  • University of Colorado Hospital, Aurora
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • University of Colorado, Aurora
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's Hospital Colorado, Aurora
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Children's Hospital Colorado, Aurora
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma

Recruiting
  • University of Colorado Hospital, Aurora
Ages 55 and older · All sexes · Updated Aug 7, 2026 · NCT07704918

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

RecruitingPhase 1/2
  • Call for Information (Investigational Site 0019), Aurora
6 Months – 17 Years · All sexes · Updated Jul 6, 2026 · NCT02332668

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

RecruitingPhase 1/2
  • University of Colorado, Anschutz Medical Campus, Aurora
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT03686124

Neoadjuvant Darovasertib in Primary Uveal Melanoma

RecruitingPhase 3
  • University of Colorado Hospital, Aurora
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

RecruitingPhase 2/3
  • University of Colorado Anschutz, Aurora
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT06624644

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06362369

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

RecruitingPhase 2/3
  • University of Colorado Hospital - Anschutz Cancer Pavilion(ACP), Aurora
All ages · All sexes · Updated Apr 2, 2026 · NCT06581406

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Rocky Mountain Cancer Centers-Aurora, Aurora
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Aurora
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Aurora

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.