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Non-Small Cell Lung Cancer clinical trials in Miami, FL

31 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Miami (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

RecruitingPhase 3
  • Miami Cancer Institute at Baptist Health, Inc. ( Site 0214), Miami
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06623422

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Miami - Sylvester Comprehensive Cancer Center, Miami
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #47, Miami
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Miami Cancer Institute, Miami
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

RecruitingPhase 3
  • Sylvester Comprehensive Cancer Center Miami, Miami
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06765109

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • Sylvester Comprehensive Cancer Center, Miami
  • Baptist Health Miami Cancer Institute, Miami
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06667076

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • University of Miami, Miami
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06667908

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Miami Cancer Institute at Baptist Health, Inc., Miami
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06890598

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

RecruitingPhase 1/2
  • Miami Cancer Institute, Miami
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07488676

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Sylvester Comprehensive Cancer Center, Miami
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • Sylvester Comprehensive Cancer Center - Miami, Miami
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

RecruitingPhase 1
  • Biogenix Molecular, LLC, Miami
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

RecruitingPhase 2/3
  • Miami Veterans Affairs Healthcare System, Miami
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • University of Miami, Miami
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Miami Cancer Institute at Baptist Health, Inc., Miami
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • University of Miami, Miami
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

RecruitingPhase 3
  • Miami Cancer Institute at Baptist Health, Miami
Ages 18 to 100 · All sexes · Updated Aug 19, 2026 · NCT05317858

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami
  • Miami Cancer Institute, Miami
  • UM Sylvester Comprehensive Cancer Center at Kendall, Miami
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer

RecruitingPhase 2
  • University of Miami, Miami
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06902272

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

RecruitingPhase 1/2
  • Sylvester Comprehensive Cancer Center, Miami
Ages 18 to 70 · All sexes · Updated Jun 11, 2026 · NCT05361174

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

RecruitingPhase 2
  • University of Miami - Sylvester Comprehensive Cancer Center, Miami
  • Bioresearch Partner, Miami
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT06463665

A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • BAPTIST ALLIANCE - MCI (Data Collection Only), Miami
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT05657873

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

A Study of VET3-TGI in Patients With Solid Tumors

RecruitingPhase 1
  • University of Miami, Miami
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06444815

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

Recruiting
  • Miami VA Healthcare System, Miami, FL, Miami
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT02984761

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Miami
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Analysis of RATS, VATS and Open Lung Resections After Neoadjuvant Chemo-immunotherapy in Patients Performed in Five Referred Centers

RecruitingObservational study
  • Baptist Health South Florida, Miami
Ages 18 and older · All sexes · Updated Nov 29, 2024 · NCT06626243

Non-Small Cell Lung Cancer trials in other cities

Other studies in Miami

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.